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Merck
CN

SETD2

SET domain containing 2

别名:
HBP231, HIF-1, HIP-1, HYPB, KMT3A, SET2, p231HBP
物种:
UniProtKB ID:
基因ID:
  • Human(29072) Summary: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]
  • Mouse(235626) SET domain containing 2
  • Rat(316013) SET domain containing 2
  • cow(539860) SET domain containing 2
  • Horse(100064888) SET domain containing 2
  • naked mole-rat(101719404) SET domain containing 2
  • domestic guinea pig(100719166) SET domain containing 2
  • chicken(420404) SET domain containing 2
  • Zebrafish(794199) SET domain containing 2
  • domestic cat(101085029) SET domain containing 2
  • dog(476643) SET domain containing 2

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Antibodies

货号
说明
物种反应性
应用
抗 SETD2 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Anti-SETD2 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunofluorescence
western blot
Anti-SETD2 antibody produced in rabbit, IgG fraction of antiserum,
物种反应性
human
应用
immunohistochemistry
western blot
Monoclonal Anti-SETD2 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL9956, purified immunoglobulin, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-SETD2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
canine, human, mouse, pig
应用
ELISA
western blot

Proteins

货号
说明
物种
Set2 human, recombinant, expressed in E. coli, ≥75% (SDS-PAGE),
物种
human
SETD2 active human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human SETD2,
物种
human
MISSION® esiRNA, targeting mouse Setd2,
物种
mouse