PTPRB
protein tyrosine phosphatase, receptor type, B
别名:
HPTP-BETA, HPTPB, PTPB, R-PTP-BETA, VEPTP
物种:
Human PTPRB (5787), Mouse Ptprb (19263), Rat Ptprb (314843), Zebrafish ptprb (100149130), chicken PTPRB (417853), domestic cat PTPRB (101100899), Horse PTPRB (100063580), dog PTPRB (481162), sheep PTPRB (101121760), cow PTPRB (505696) ...展开
UniProtKB ID:
基因ID:
- Human(5787) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and one intracytoplasmic catalytic domain, thus belongs to receptor type PTP. The extracellular region of this PTP is composed of multiple fibronectin type_III repeats, which was shown to interact with neuronal receptor and cell adhesion molecules, such as contactin and tenascin C. This protein was also found to interact with sodium channels, and thus may regulate sodium channels by altering tyrosine phosphorylation status. The functions of the interaction partners of this protein implicate the roles of this PTP in cell adhesion, neurite growth, and neuronal differentiation. Alternate transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
- Mouse(19263) protein tyrosine phosphatase, receptor type, B
- Rat(314843) protein tyrosine phosphatase, receptor type, B
- Zebrafish(100149130) protein tyrosine phosphatase, receptor type, b
- chicken(417853) protein tyrosine phosphatase, receptor type, B
- domestic cat(101100899) protein tyrosine phosphatase, receptor type, B
- Horse(100063580) protein tyrosine phosphatase, receptor type, B
- dog(481162) protein tyrosine phosphatase, receptor type, B
- sheep(101121760) protein tyrosine phosphatase, receptor type, B
- cow(505696) protein tyrosine phosphatase, receptor type, B
- naked mole-rat(101721226) protein tyrosine phosphatase, receptor type, B
- domestic guinea pig(100720273) protein tyrosine phosphatase, receptor type, B
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Antibodies
货号
说明
物种反应性
应用
Anti-PTPβ (C-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
物种反应性
human
应用
ELISA
Proteins
货号
说明
物种
PTP-β human, ≥90%, recombinant, expressed in E. coli K12, GST-tagged, buffered aqueous glycerol solution, ≥50,000 units/mg protein,
物种
human
esiRNA
货号
说明
物种