PRG4
proteoglycan 4
CACP, HAPO, JCAP, MSF, SZP, bG174L6.2
Human PRG4 (23572), Human PRG4 (10216), Mouse Prg4 (96875), Rat Prg4 (289104), domestic guinea pig Prg4 (100716004), sheep PRG4 (100294585), cow PRG4 (280867), Domestic Rabbit PRG4 (100328909), sheep PRG4 (101110076), naked mole-rat Prg4 (101697808) ...展开
- Human(23572) Summary: The protein encoded by this gene is a large proteoglycan specifically synthesized by chondrocytes located at the surface of articular cartilage, and also by some synovial lining cells. This protein contains both chondroitin sulfate and keratan sulfate glycosaminoglycans. It functions as a boundary lubricant at the cartilage surface and contributes to the elastic absorption and energy dissipation of synovial fluid. Mutations in this gene result in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Human(10216) Summary: The protein encoded by this gene is a large proteoglycan specifically synthesized by chondrocytes located at the surface of articular cartilage, and also by some synovial lining cells. This protein contains both chondroitin sulfate and keratan sulfate glycosaminoglycans. It functions as a boundary lubricant at the cartilage surface and contributes to the elastic absorption and energy dissipation of synovial fluid. Mutations in this gene result in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(96875) proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
- Rat(289104) proteoglycan 4
- domestic guinea pig(100716004) proteoglycan 4
- sheep(100294585) proteoglycan 4
- cow(280867) proteoglycan 4
- Domestic Rabbit(100328909) proteoglycan 4
- sheep(101110076) proteoglycan 4
- naked mole-rat(101697808) proteoglycan 4
- Horse(100034016) proteoglycan 4
- chicken(768493) proteoglycan 4
- domestic cat(101085684) proteoglycan 4
- dog(664716) proteoglycan 4
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Antibodies
Anti-Lubricin/PRG4 Antibody, clone 1C20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
human, mouse, rat
affinity binding assay
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Lubricin/PRG4 Antibody, clone 9G3 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
human, rat
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
抗-润滑素/蛋白聚糖4,克隆5C11抗体, clone 5C11, from mouse,
bovine, canine, goat, guinea pig, human, porcine, rat
immunohistochemistry
western blot
western blot