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PCSK9

proprotein convertase subtilisin/kexin type 9

Synonyms:
FH3, HCHOLA3, LDLCQ1, NARC-1, NARC1, PC9
Species:
UniProtKB ID:
Gene ID:
  • Human(255738) Summary: This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia (HCHOLA3). [provided by RefSeq, Jul 2008]
  • Mouse(100102) proprotein convertase subtilisin/kexin type 9
  • Rat(298296) proprotein convertase subtilisin/kexin type 9
  • Zebrafish(100150316) proprotein convertase subtilisin/kexin type 9
  • domestic guinea pig(100731533) proprotein convertase subtilisin/kexin type 9
  • chicken(424664) proprotein convertase subtilisin/kexin type 9
  • naked mole-rat(101700911) proprotein convertase subtilisin/kexin type 9

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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ELISA

Product Number
Description
Species
Human Proprotein Convertase 9 ELISA, for serum, plasma and cell culture supernatants,
Species
human

Activity Assay

Product Number
Description
Species
Alpaca Anti-PCSK9, recombinant single domain Antibody, Recombinant Alpaca(VHH) Nano antibody,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PCSK9 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
[KD Validated]Anti-PCSK9 Antibody, clone 9L4U5, Rabbit Monoclonal, ,
Species Reactivity
human
Application
western blot
Anti-PCSK9 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human
Application
immunocytochemistry
western blot
Anti-PCSK9 Antibody, clone 9B3.1, culture supernatant, clone 9B3.1, from mouse,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-NARC-1 Antibody, serum, Chemicon®,
Species Reactivity
mouse
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PCSK9,
Species
human
MISSION® esiRNA, targeting mouse Pcsk9,
Species
mouse