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Merck
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NOTCH3

notch 3

别名:
CADASIL, CASIL, IMF2
物种:
UniProtKB ID:
基因ID:
  • Human(4854) Summary: This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq, Jul 2008]
  • Mouse(18131) notch 3
  • Rat(56761) notch 3
  • domestic guinea pig(100716867) notch 3
  • naked mole-rat(101722220) notch 3
  • Zebrafish(58066) notch homolog 3
  • dog(610439) notch 3
  • domestic cat(101088469) notch 3
  • sheep(101123554) notch 3
  • cow(789485) notch 3

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ELISA

货号
说明
物种
人Notch-3 ELISA, for serum, plasma and cell culture supernatants,
物种
human

Antibodies

货号
说明
物种反应性
应用
Anti-Notch3 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
抗-NOTCH 3/N3ECD抗体,克隆1E4, clone 1E4, 1 mg/mL, from mouse,
物种反应性
human
应用
electron microscopy
immunocytochemistry

western blot
Monoclonal Anti-NOTCH3 antibody produced in mouse, clone 2E2, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunofluorescence

western blot
Anti-NOTCH3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
Anti-Notch 3 Antibody, clone 1G17 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, mouse, rat
应用
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot

Small Molecule - Inhibitor

货号
说明
物种
DAPT, ≥98% (HPLC), solid,
物种
mouse, human, rat
L-685,458, >96% (HPLC), solid,
物种
mouse, human, rat

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Notch3,
物种
mouse
MISSION® esiRNA, targeting human NOTCH3,
物种
human