MYLK
myosin light chain kinase
别名:
AAT7, KRP, MLCK, MLCK1, MLCK108, MLCK210, MSTP083, MYLK1, smMLCK
物种:
Human MYLK (4638), Mouse Mylk (107589), Rat Mylk (288057), domestic guinea pig Mylk (100714177), dog MYLK (488012), naked mole-rat Mylk (101704236), chicken MYLK (396445), Domestic Rabbit MYLK (100009143), sheep MYLK (443334), cow MYLK (338037)
UniProtKB ID:
基因ID:
- Human(4638) Summary: This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts. [provided by RefSeq, Jul 2008]
- Mouse(107589) myosin, light polypeptide kinase
- Rat(288057) myosin light chain kinase
- domestic guinea pig(100714177) myosin light chain kinase
- dog(488012) myosin light chain kinase
- naked mole-rat(101704236) myosin light chain kinase
- chicken(396445) myosin light chain kinase
- Domestic Rabbit(100009143) myosin light chain kinase
- sheep(443334) myosin light chain kinase
- cow(338037) myosin light chain kinase
- Horse(100070482) myosin light chain kinase
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Antibodies
货号
说明
物种反应性
应用
单克隆抗肌球蛋白轻链激酶 小鼠抗, clone K36, ascites fluid,
物种反应性
avian, mammals
应用
immunoprecipitation (IP)
microarray
western blot
microarray
western blot
Anti-MYLK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
western blot
Monoclonal Anti-MYLK antibody produced in mouse, clone 1D1, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
western blot
Anti-MYLK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-MYLK antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
human, mouse
应用
ELISA
western blot
western blot
Small Molecule - Inhibitor
货号
说明
物种
Proteins
货号
说明
物种
MLCK Protein, active, 10 µg, Active, N-terminal 6His-tagged, recombinant, human MLCK, amino acids 1425-1771, for use in Kinase Assays.,
物种
human
MLCK (1425-1776)，活性，GST 标记 人, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human