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MRE11A

MRE11 meiotic recombination 11 homolog A (S. cerevisiae)

别名:
ATLD, HNGS1, MRE11, MRE11B
物种:
UniProtKB ID:
基因ID:
  • Human(4361) Summary: This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(17535) meiotic recombination 11 homolog A (S. cerevisiae)
  • Rat(64046) MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
  • domestic guinea pig(100721147) MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
  • naked mole-rat(101709211) MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
  • Domestic Rabbit(100356946) MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
  • sheep(101114806) MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
  • Horse(100060936) MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
  • domestic cat(101086923) MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
  • dog(494006) MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
  • Zebrafish(406637) meiotic recombination 11 homolog A (S. cerevisiae)
  • chicken(395555) MRE11 meiotic recombination 11 homolog A (S. cerevisiae)

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Antibodies

货号
说明
物种反应性
应用
Anti-MRE11 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry

western blot
Anti-MRE11A antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunoprecipitation (IP)

western blot
Monoclonal Anti-MRE11A antibody produced in mouse, clone 3H4-F4, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
Monoclonal Anti-MRE11A antibody produced in mouse, clone 1D8-A6, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot

Small Molecule - Inhibitor

货号
说明
物种
Mirin, ≥98% (HPLC), powder,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Mre11a,
物种
mouse
MISSION® esiRNA, targeting human MRE11,
物种
human