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MMP14

matrix metallopeptidase 14 (membrane-inserted)

别名:
MMP-14, MMP-X1, MT-MMP, MT-MMP 1, MT1-MMP, MT1MMP, MTMMP1
物种:
UniProtKB ID:
基因ID:
  • Human(4323) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. [provided by RefSeq, Jul 2008]
  • Mouse(17387) matrix metallopeptidase 14 (membrane-inserted)
  • Rat(81707) matrix metallopeptidase 14 (membrane-inserted)
  • naked mole-rat(101723795) matrix metallopeptidase 14 (membrane-inserted)
  • sheep(443116) matrix metallopeptidase 14 (membrane-inserted)
  • cow(281915) matrix metallopeptidase 14 (membrane-inserted)
  • Domestic Rabbit(100009598) matrix metallopeptidase 14 (membrane-inserted)
  • domestic guinea pig(100732039) matrix metallopeptidase 14 (membrane-inserted)
  • dog(403823) matrix metallopeptidase 14 (membrane-inserted)
  • Horse(100034170) matrix metallopeptidase 14 (membrane-inserted)
  • domestic cat(101089776) matrix metallopeptidase 14 (membrane-inserted)
  • chicken(426253) matrix metallopeptidase 14 (membrane-inserted)

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Antibodies

货号
说明
物种反应性
应用
抗MMP-14抗体,催化域,克隆LEM-2 / 15.8, clone LEM-2/15.8, Chemicon®, from mouse,
物种反应性
human, mouse
应用
ELISA
immunoprecipitation (IP)

western blot
Anti-MMP-14 Antibody, catalytic domain, clone LEM-2/63.1, clone LEM-2/63.1, Chemicon®, from mouse,
物种反应性
mouse
应用
ELISA
immunoprecipitation (IP)

western blot
Anti-MMP-14 Antibody, serum, Chemicon®,
物种反应性
human
应用
ELISA
flow cytometry

immunocytochemistry

immunoprecipitation (IP)

western blot
Anti-MMP-14 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry

western blot
Anti-MMP14 (Cleaved-Tyr112) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
western blot

Small Molecule - Inhibitor

货号
说明
物种
马立马司他, ≥98% (HPLC),
物种
human, rat, mouse
CP-101537, ≥98% (HPLC),
物种
human, rat, mouse
CP-471474, ≥98% (HPLC),
物种
human, rat, mouse
PD166793 hydrate, ≥98% (HPLC),
物种
human, rat, mouse

Proteins

货号
说明
物种
MMP-14, human, prodomain, catalytic domain, and hemopexin domain, E. coli recombinant, ,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human MMP14,
物种
human
MISSION® esiRNA, targeting mouse Mmp14,
物种
mouse