跳转至内容
Merck
CN

LEPR

leptin receptor

别名:
CD295, LEP-R, LEPRD, OB-R, OBR
物种:
UniProtKB ID:
基因ID:
  • Human(3953) Summary: The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).[provided by RefSeq, Nov 2010]
  • Mouse(16847) leptin receptor
  • Rat(24536) leptin receptor
  • domestic cat(101085646) leptin receptor
  • Zebrafish(567241) leptin receptor
  • chicken(374223) leptin receptor
  • sheep(443264) leptin receptor
  • domestic guinea pig(100725434) leptin receptor
  • naked mole-rat(101705981) leptin receptor
  • Horse(100033894) leptin receptor
  • cow(497205) leptin receptor
  • dog(450207) leptin receptor

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

货号
说明
物种
小鼠Lepr / Leptin受体ELISA试剂盒, ,
物种
mouse

Antibodies

货号
说明
物种反应性
应用
Anti-LEPR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-Leptin Receptor antibody produced in goat, affinity isolated antibody, lyophilized powder,
物种反应性
mouse
应用
flow cytometry
immunohistochemistry

western blot
Anti-Leptin Receptor antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunohistochemistry

western blot
Anti-Leptin Receptor Antibody, clone 6I0O4, Rabbit Monoclonal, ,
物种反应性
human, rat
应用
immunohistochemistry
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human LEPR (2),
物种
human
MISSION® esiRNA, targeting human LEPR,
物种
human
MISSION® esiRNA, targeting mouse Lepr,
物种
mouse