跳转至内容
Merck
CN

LEF1

lymphoid enhancer-binding factor 1

别名:
LEF-1, TCF10, TCF1ALPHA, TCF7L3
物种:
UniProtKB ID:
基因ID:
  • Human(51176) Summary: This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
  • Mouse(16842) lymphoid enhancer binding factor 1
  • Rat(161452) lymphoid enhancer binding factor 1
  • domestic guinea pig(100716066) lymphoid enhancer-binding factor 1
  • naked mole-rat(101711023) lymphoid enhancer-binding factor 1
  • dog(478507) lymphoid enhancer-binding factor 1
  • Zebrafish(30701) lymphocyte enhancer binding factor 1
  • domestic cat(101088077) lymphoid enhancer-binding factor 1
  • cow(535399) lymphoid enhancer-binding factor 1
  • chicken(395865) lymphoid enhancer-binding factor 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

货号
说明
物种反应性
应用
ChIPAb+ LEF1 - ChIP经验证的抗体和引物组, from mouse,
物种反应性
human, mouse
应用
ChIP
western blot
Anti-LEF1 (AB1) antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, goat, human
应用
western blot
Anti-LEF1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-LEF1 antibody produced in mouse, clone 5A3, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunofluorescence

western blot
Anti-LEF1 (AB2) antibody produced in rabbit, IgG fraction of antiserum,
物种反应性
bovine, dog, goat, guinea pig, horse, human, mouse, rabbit, rat
应用
immunohistochemistry
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human LEF1,
物种
human