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Merck
CN

IL10RA

interleukin 10 receptor, alpha

别名:
CD210, CD210a, CDW210A, HIL-10R, IL-10R1, IL10R
物种:
UniProtKB ID:
基因ID:
  • Human(3587) Summary: The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2009]
  • Mouse(16154) interleukin 10 receptor, alpha
  • Rat(117539) interleukin 10 receptor, alpha
  • sheep(101120946) interleukin 10 receptor, alpha
  • domestic guinea pig(100727507) interleukin 10 receptor, alpha
  • dog(610823) interleukin 10 receptor, alpha
  • naked mole-rat(101706532) interleukin 10 receptor, alpha
  • Zebrafish(777651) interleukin 10 receptor, alpha
  • domestic cat(101087601) interleukin 10 receptor, alpha
  • cow(513478) interleukin 10 receptor, alpha
  • chicken(419771) interleukin 10 receptor, alpha

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Antibodies

货号
说明
物种反应性
应用
Monoclonal Anti-Interleukin-10 Receptor α antibody produced in mouse, clone 37607, purified immunoglobulin, lyophilized powder,
物种反应性
human
应用
neutralization
Anti-IL-10R α antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
immunofluorescence

western blot
Monoclonal Anti-IL10RA antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL8203, purified immunoglobulin, buffered aqueous glycerol solution,
物种反应性
human
应用
western blot
Anti-IL10RA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
Anti-IL10RA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
western blot