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Merck
CN

IDH3G

isocitrate dehydrogenase 3 (NAD+) gamma

别名:
H-IDHG
物种:
UniProtKB ID:
基因ID:
  • Human(3421) Summary: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the gamma subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. This gene is a candidate gene for periventricular heterotopia. Several alternatively spliced transcript variants of this gene have been described, but only some of their full length natures have been determined. [provided by RefSeq, Jul 2008]
  • Mouse(15929) isocitrate dehydrogenase 3 (NAD+), gamma
  • Rat(25179) isocitrate dehydrogenase 3 (NAD), gamma
  • cow(614145) isocitrate dehydrogenase 3 (NAD+) gamma
  • Zebrafish(550408) isocitrate dehydrogenase 3 (NAD+) gamma
  • sheep(101110910) isocitrate dehydrogenase 3 (NAD+) gamma
  • Domestic Rabbit(100328743) isocitrate dehydrogenase 3 (NAD+) gamma
  • dog(481081) isocitrate dehydrogenase 3 (NAD+) gamma

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Antibodies

货号
说明
物种反应性
应用
Anti-IDH3G antibody produced in rabbit, Ab2, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry

western blot
Anti-IDH3G antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry

western blot
Anti-IDH3G antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human, rat
应用
western blot
Monoclonal Anti-IDH3G antibody produced in mouse, clone 2A2-1D3, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
Anti-IDH3G antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot

Kits

货号
说明
物种
IDH 活性检测试剂盒, sufficient for 100 colorimetric tests,
物种
mouse, rat, human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human IDH3G,
物种
human