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Merck
CN

HTR3B

5-hydroxytryptamine (serotonin) receptor 3B, ionotropic

别名:
5-HT3B
物种:
Human HTR3B (9177), Mouse Htr3b (57014), Rat Htr3b (58963), domestic cat HTR3B (101082340), sheep HTR3B (101110267), cow HTR3B (541055), naked mole-rat Htr3b (101726074), domestic guinea pig Htr3b (100736034), dog HTR3B (611236)
UniProtKB ID:
O95264, B0YJ23, Q0VJC3
基因ID:
  • Human(9177) Summary: The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit B of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It is not functional as a homomeric complex, but a pentaheteromeric complex with subunit A (HTR3A) displays the full functional features of this receptor. [provided by RefSeq, Aug 2011]
  • Mouse(57014) 5-hydroxytryptamine (serotonin) receptor 3B
  • Rat(58963) 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
  • domestic cat(101082340) 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
  • sheep(101110267) 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
  • cow(541055) 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
  • naked mole-rat(101726074) 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
  • domestic guinea pig(100736034) 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
  • dog(611236) 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic

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Small Molecule - Agonist

货号
说明
物种
S1688
SR 57227A, solid,
物种
human
M0763
甲氧氯普胺 盐酸盐, solid,
物种
human
Q1004
喹哌嗪 马来酸盐, ,
物种
human

Small Molecule - Allosteric Modulator

货号
说明
物种
D9190
DCEBIO, ≥98% (HPLC), solid,
物种
human

Small Molecule - Antagonist

货号
说明
物种
M0763
甲氧氯普胺 盐酸盐, solid,
物种
human
BP1090
氨磺必利, British Pharmacopoeia (BP) Reference Standard,
物种
human
A0590000
氨磺必利, European Pharmacopoeia (EP) Reference Standard,
物种
human
BP1143
系统适用性试验用氨磺必利, British Pharmacopoeia (BP) Reference Standard,
物种
human
Y0001534
氨磺必利, European Pharmacopoeia (EP) Reference Standard,
物种
human

Antibodies

货号
说明
物种反应性
应用
SAB2107925
Anti-HTR3B antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
western blot
HPA039559
Anti-HTR3B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
SAB1401455
Anti-HTR3B antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot

Small Molecule - Blocker

货号
说明
物种
T3146
三甲丙咪嗪标准液 马来酸盐, ≥98% (TLC), powder,
物种
human

Small Molecule - Inhibitor

货号
说明
物种
F1553
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
物种
human
F1678
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
物种
human
F132
氟西汀 盐酸盐, solid,
物种
human
S6319
盐酸舍曲林 盐酸盐, ≥98% (HPLC),
物种
human
C7861
氢溴酸西酞普兰 氢溴酸盐, ≥98% (HPLC),
物种
human

Small Molecule - Ligand

货号
说明
物种
M1514
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
物种
human

Small Molecule - Metabolite

货号
说明
物种
H8876
5-羟基吲哚-3-乙酸, ≥98% (HPLC), crystalline,
物种
human

Small Molecule - Precursor

货号
说明
物种
H9772
5-羟基L-色氨酸, powder,
物种
human

esiRNA

货号
说明
物种
EMU014241
MISSION® esiRNA, targeting mouse Htr3b,
物种
mouse