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HHIP

hedgehog interacting protein

别名:
HIP
物种:
UniProtKB ID:
基因ID:
  • Human(64399) Summary: This gene encodes a member of the hedgehog-interacting protein (HHIP) family. The hedgehog (HH) proteins are evolutionarily conserved protein, which are important morphogens for a wide range of developmental processes, including anteroposterior patterns of limbs and regulation of left-right asymmetry in embryonic development. Multiple cell-surface receptors are responsible for transducing and/or regulating HH signals. The HHIP encoded by this gene is a highly conserved, vertebrate-specific inhibitor of HH signaling. It interacts with all three HH family members, SHH, IHH and DHH. Two single nucleotide polymorphisms (SNPs) near this gene are significantly associated with risk of chronic obstructive pulmonary disease (COPD). A single nucleotide polymorphism in this gene is also strongly associated with human height.[provided by RefSeq, Feb 2011]
  • Mouse(15245) Hedgehog-interacting protein
  • Rat(291936) Hedgehog-interacting protein
  • Domestic Rabbit(100344588) hedgehog interacting protein
  • domestic cat(101087058) hedgehog interacting protein
  • sheep(101111396) hedgehog interacting protein
  • cow(540830) hedgehog interacting protein
  • chicken(422460) hedgehog interacting protein
  • Zebrafish(326102) hedgehog interacting protein
  • naked mole-rat(101724427) hedgehog interacting protein
  • dog(475452) hedgehog interacting protein
  • Horse(100062868) hedgehog interacting protein
  • domestic guinea pig(100728644) hedgehog interacting protein

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Antibodies

货号
说明
物种反应性
应用
Monoclonal Anti-HHIP antibody produced in mouse, clone 5D11, purified immunoglobulin, buffered aqueous solution,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry

immunoprecipitation (IP)

western blot
抗-HHIP 兔抗, ,
物种反应性
chicken, human, mouse
应用
immunocytochemistry
immunofluorescence

immunohistochemistry

western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Hhip,
物种
mouse
MISSION® esiRNA, targeting human HHIP,
物种
human