FBXL4
F-box and leucine-rich repeat protein 4
- Human(26235) Summary: This gene encodes a member of the F-box protein family, which are characterized by an approximately 40 amino acid motif, the F-box. F-box proteins constitute one subunit of modular E3 ubiquitin ligase complexes, called SCF complexes, which function in phosphorylation-dependent ubiquitination. The F-box domain mediates protein-protein interactions and binds directly to S-phase kinase-associated protein 1. In addition to an F-box domain, the encoded protein contains at least 9 tandem leucine-rich repeats. The ubiquitin ligase complex containing the encoded protein may function in cell-cycle control by regulating levels of lysine-specific demethylase 4A. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
- Mouse(269514) F-box and leucine-rich repeat protein 4
- Rat(313101) F-box and leucine-rich repeat protein 4
- Zebrafish(492349) F-box and leucine-rich repeat protein 4
- fruit fly(32378) F box and leucine-rich-repeat gene 4
- cow(535452) F-box and leucine-rich repeat protein 4
- Horse(100066051) F-box and leucine-rich repeat protein 4
- naked mole-rat(101717262) F-box and leucine-rich repeat protein 4
- chicken(421798) F-box and leucine-rich repeat protein 4
- domestic cat(101083680) F-box and leucine-rich repeat protein 4
- sheep(101104499) F-box and leucine-rich repeat protein 4
- dog(481932) F-box and leucine-rich repeat protein 4
- domestic guinea pig(100723716) F-box and leucine-rich repeat protein 4
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