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EIF2AK3

eukaryotic translation initiation factor 2-alpha kinase 3

别名:
PEK, PERK, WRS
物种:
Human EIF2AK3 (9451), Mouse Eif2ak3 (13666), Rat Eif2ak3 (29702), Horse EIF2AK3 (100066488), domestic cat EIF2AK3 (101095973), cow EIF2AK3 (535820), Zebrafish eif2ak3 (559564), dog EIF2AK3 (475756), chicken EIF2AK3 (422930), sheep EIF2AK3 (101110042) ...展开
UniProtKB ID:
Q9NZJ5, A0AVH1, A0AVH2, B2RCU9, O95846, Q53QY0, Q53SB1
基因ID:
  • Human(9451) Summary: The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Jan 2010]
  • Mouse(13666) eukaryotic translation initiation factor 2 alpha kinase 3
  • Rat(29702) eukaryotic translation initiation factor 2 alpha kinase 3
  • Horse(100066488) eukaryotic translation initiation factor 2-alpha kinase 3
  • domestic cat(101095973) eukaryotic translation initiation factor 2-alpha kinase 3
  • cow(535820) eukaryotic translation initiation factor 2-alpha kinase 3
  • Zebrafish(559564) eukaryotic translation initiation factor 2-alpha kinase 3
  • dog(475756) eukaryotic translation initiation factor 2-alpha kinase 3
  • chicken(422930) eukaryotic translation initiation factor 2-alpha kinase 3
  • sheep(101110042) eukaryotic translation initiation factor 2-alpha kinase 3
  • domestic guinea pig(100725836) eukaryotic translation initiation factor 2-alpha kinase 3
  • naked mole-rat(101713561) eukaryotic translation initiation factor 2-alpha kinase 3

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Antibodies

货号
说明
物种反应性
应用
SAB5700521
Anti-Phospho-PERK-T982 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
western blot
SAB4301310
抗-磷酸化-PEK/PERK (pThr981) 兔抗, affinity isolated antibody,
物种反应性
human
应用
immunohistochemistry
MABN842
Anti-PERK Antibody, clone 4F6.1, clone 4F6.1, from mouse,
物种反应性
human
应用
immunohistochemistry
western blot
HPA015737
Anti-EIF2AK3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
SAB4503650
Anti-E2AK3 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
immunofluorescence
western blot

Cell Lines

货号
说明
物种
MTOX1024
HepaRG™ Cells PERK (-/-), one vial,
物种
human

Proteins

货号
说明
物种
SRP5024
EIF2AK3 (563-1115), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human
14-916-M
PEK, active, ,
物种
human
14-916
PEK Protein, active, 10 µg, ,
物种
human

esiRNA

货号
说明
物种
EMU014751
MISSION® esiRNA, targeting mouse Eif2ak3,
物种
mouse
EHU030881
MISSION® esiRNA, targeting human EIF2AK3, AC104134.2,
物种
human