DNMT3B
DNA (cytosine-5-)-methyltransferase 3 beta
别名:
ICF, ICF1, M.HsaIIIB
物种:
Human DNMT3B (1789), Mouse Dnmt3b (13436), Rat Dnmt3b (444985), domestic guinea pig Dnmt3b (100731772), naked mole-rat Dnmt3b (101725788), dog DNMT3B (100685634), Horse DNMT3B (100053900), domestic cat DNMT3B (101092926), cow DNMT3B (353354), Domestic Rabbit DNMT3B (100349823) ...展开
UniProtKB ID:
基因ID:
- Human(1789) Summary: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined. [provided by RefSeq, May 2011]
- Mouse(13436) DNA methyltransferase 3B
- Rat(444985) DNA (cytosine-5-)-methyltransferase 3 beta
- domestic guinea pig(100731772) DNA (cytosine-5-)-methyltransferase 3 beta
- naked mole-rat(101725788) DNA (cytosine-5-)-methyltransferase 3 beta
- dog(100685634) DNA (cytosine-5-)-methyltransferase 3 beta
- Horse(100053900) DNA (cytosine-5-)-methyltransferase 3 beta
- domestic cat(101092926) DNA (cytosine-5-)-methyltransferase 3 beta
- cow(353354) DNA (cytosine-5-)-methyltransferase 3 beta
- Domestic Rabbit(100349823) DNA (cytosine-5-)-methyltransferase 3 beta
- sheep(100500777) DNA (cytosine-5-)-methyltransferase 3 beta
- Zebrafish(321084) DNA (cytosine-5-)-methyltransferase 3 beta
- chicken(419287) DNA (cytosine-5-)-methyltransferase 3 beta
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Antibodies
货号
说明
物种反应性
应用
Anti-DNMT3B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-DNMT3B antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-DNMT3B antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
应用
western blot
Anti-Dnmt3b Antibody, clone D3B2-2C1, clone D3B2-2C1, from rat,
物种反应性
human
应用
immunoprecipitation (IP)
western blot
western blot
Anti-DNMT3B Antibody, clone 2N12 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, monkey
应用
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Small Molecule - Inhibitor
货号
说明
物种
Proteins
货号
说明
物种
DNMT3B/DNMT3L Active human, recombinant, expressed in baculovirus infected insect cells, ≥90% (SDS-PAGE),
物种
human
esiRNA
货号
说明
物种