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Merck
CN

CNR2

cannabinoid receptor 2 (macrophage)

别名:
CB-2, CB2, CX5
物种:
UniProtKB ID:
基因ID:
  • Human(1269) Summary: The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors. [provided by RefSeq, Jul 2008]
  • Mouse(12802) cannabinoid receptor 2 (macrophage)
  • Rat(57302) cannabinoid receptor 2 (macrophage)
  • chicken(428232) cannabinoid receptor 2 (macrophage)
  • Horse(100071536) cannabinoid receptor 2 (macrophage)
  • domestic cat(101100234) cannabinoid receptor 2 (macrophage)
  • dog(612289) cannabinoid receptor 2 (macrophage)
  • cow(539769) cannabinoid receptor 2 (macrophage)
  • sheep(101119188) cannabinoid receptor 2 (macrophage)
  • domestic guinea pig(100721528) cannabinoid receptor 2 (macrophage)
  • Zebrafish(795246) cannabinoid receptor 2

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Small Molecule - Agonist

货号
说明
物种
( R )-(+)-WIN 55,212-2 甲磺酸盐, ≥98% (HPLC),
物种
human
花生四烯酸-2′-氯乙酰胺 水合物, ≥97% (HPLC), oil,
物种
rat, mouse
油酰单乙醇胺, ~98% (TLC),
物种
human, mouse, rat

Small Molecule - Antagonist

货号
说明
物种
棕榈酸甲酯, ≥99% (capillary GC),
物种
human, rat
棕榈酰, ,
物种
human, rat
AM251, >98% (HPLC), solid,
物种
mouse, rat
2-花生四烯基甘油, ~10 mg/mL, ≥98% (HPLC),
物种
rat, human
棕榈酸异丙酯, technical grade, 90%,
物种
human, rat

Antibodies

货号
说明
物种反应性
应用
Monoclonal Anti-CNR2 antibody produced in mouse, clone 3C7, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunofluorescence

western blot
Anti-CNR2 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
western blot
Anti-Cannabinoid Receptor 2 antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human, rat
应用
immunocytochemistry
western blot

Small Molecule - Mixed Agonist/Antagonist

货号
说明
物种
CP-55940, >98% (HPLC), powder,
物种
human, rat
棕榈酰, ,
物种
human, rat

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human CNR2,
物种
human