推荐产品
生物来源
synthetic
质量水平
无菌性
non-sterile
检测方案
≥98% (HPLC)
形式
powder
技术
cell culture | mammalian: suitable
mp
223 °C (dec.) (lit.)
溶解性
4 M NH4OH in methanol: 50 mg/mL, clear to hazy, yellow
运输
ambient
储存温度
room temp
SMILES字符串
N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C(O)=O
InChI
1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23)/t12-/m0/s1
InChI key
XUIIKFGFIJCVMT-LBPRGKRZSA-N
基因信息
human ... THRA(7067) , THRB(7068) , TTR(7276)
mouse ... Cnr2(12802)
rat ... Cnr1(25248)
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相关类别
应用
L-甲状腺素用于研究光诱导的 T4 到 T3 的激素转化在对日本鹌鹑性腺的光周期反应的调节作用。该产品用作测试化合物,用于研究多种激素对培养的大鼠睾丸细胞表面形态的影响。
生化/生理作用
甲状腺素是一种含碘激素,由甲状腺滤泡细胞中的甲状腺球蛋白产生。L-甲状腺素可降低亚临床甲状腺功能减退症患者的总胆固醇水平、低密度脂蛋白胆固醇以及腰臀比。因此,有助于改善心血管危险因素以及能增强疲劳症状。
L甲状腺素 (T4) 和三碘代-L-甲状腺原氨酸 (T3) 为含碘激素,由甲状腺卵泡细胞中的甲状腺球蛋白制备。这些激素对代谢率的刺激以及对生长发展的调节似乎归因于它们对 DNA 转录的作用,进而影响蛋白质的合成。
包装
无底玻璃瓶。内含物装在插入的融合锥内。
制备说明
L-甲状腺素溶于 4M 甲醇的氢氧化铵溶液中,浓度为 50 mg/ml,得到澄清至浑浊的黄色至暗黄色溶液。
警示用语:
Danger
危险声明
危险分类
STOT RE 1
靶器官
Thyroid,Cardio-vascular system,Kidney
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
监管及禁止进口产品
PeerJ, 8, e10175-e10175 (2020-10-23)
Maternal thyroid hormones (THs) are known to be crucial in embryonic development in humans, but their influence on other, especially wild, animals remains poorly understood. So far, the studies that experimentally investigated the consequences of maternal THs focused on short-term
The American journal of anatomy, 151(1), 55-69 (1978-01-01)
The purpose of this investigation was to study the effects of various hormones on the surface morphology of 20-day-old rat testicular cells in culture. Aggregates containing primarily Sertoli cells and germinal cells were obtained by enzymatic digestion. The surface morphology
Data in brief, 29, 105179-105179 (2020-02-15)
The presented data article reports protein expression profiles during a time course of limb regeneration in the highly regenerative neotenic and regeneration-deficient metamorphic axolotl (Ambystoma mexicanum). A protein database was first generated from transcriptome data, which was used concomitantly with
Nature, 426(6963), 178-181 (2003-11-14)
Reproduction of many temperate zone birds is under photoperiodic control. The Japanese quail is an excellent model for studying the mechanism of photoperiodic time measurement because of its distinct and marked response to changing photoperiods. Studies on this animal have
The Journal of clinical endocrinology and metabolism, 92(5), 1715-1723 (2007-02-15)
Subclinical hypothyroidism (SCH) is defined as raised serum TSH levels with circulating thyroid hormones within the reference range. It is uncertain whether treatment of SCH with L-thyroxine improves cardiovascular (CV) risk factors and quality of life. The objective of the
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