BMPR2
bone morphogenetic protein receptor, type II (serine/threonine kinase)
别名:
BMPR-II, BMPR3, BMR2, BRK-3, PPH1, T-ALK
物种:
Human BMPR2 (659), Mouse Bmpr2 (12168), Rat Bmpr2 (140590), cow BMPR2 (407127), naked mole-rat Bmpr2 (101701138), Domestic Rabbit BMPR2 (100350246), sheep BMPR2 (101103793), domestic guinea pig Bmpr2 (100736232), chicken BMPR2 (374147), sheep BMPR2 (100294556) ...展开
UniProtKB ID:
基因ID:
- Human(659) Summary: This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq, Jul 2008]
- Mouse(12168) bone morphogenetic protein receptor, type II (serine/threonine kinase)
- Rat(140590) bone morphogenetic protein receptor, type II (serine/threonine kinase)
- cow(407127) bone morphogenetic protein receptor, type II (serine/threonine kinase)
- naked mole-rat(101701138) bone morphogenetic protein receptor, type II (serine/threonine kinase)
- Domestic Rabbit(100350246) bone morphogenetic protein receptor, type II (serine/threonine kinase)
- sheep(101103793) bone morphogenetic protein receptor, type II (serine/threonine kinase)
- domestic guinea pig(100736232) bone morphogenetic protein receptor, type II (serine/threonine kinase)
- chicken(374147) bone morphogenetic protein receptor, type II (serine/threonine kinase)
- sheep(100294556) bone morphogenetic protein receptor, type II (serine/threonine kinase)
- domestic cat(101096338) bone morphogenetic protein receptor, type II (serine/threonine kinase)
- dog(478875) bone morphogenetic protein receptor, type II (serine/threonine kinase)
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ELISA
货号
说明
物种
Antibodies
货号
说明
物种反应性
应用
Anti-BMPR2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Monoclonal Anti-BMPR2 antibody produced in mouse, clone 3F6, ascites fluid,
物种反应性
human, monkey, mouse, rat
应用
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-BMPR2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-BMR2 Antibody, clone 3F6, ascites fluid, clone 3F6, from mouse,
物种反应性
human, monkey, mouse, rat
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-BMPR-II Antibody, clone 9F4.1, clone 9F4.1, from mouse,
物种反应性
human
应用
immunohistochemistry
western blot
western blot
Proteins
货号
说明
物种
BMPR2 (174-end), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human