ADAMTS4
ADAM metallopeptidase with thrombospondin type 1 motif, 4
别名:
ADAMTS-2, ADAMTS-4, ADMP-1
物种:
Human ADAMTS4 (9507), Mouse Adamts4 (240913), Rat Adamts4 (66015), domestic cat ADAMTS4 (101089488), Horse ADAMTS4 (100033914), dog ADAMTS4 (488651), sheep ADAMTS4 (101106565), cow ADAMTS4 (286806), naked mole-rat Adamts4 (101702362), domestic guinea pig Adamts4 (100712995)
UniProtKB ID:
基因ID:
- Human(9507) Summary: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma. [provided by RefSeq, Jul 2008]
- Mouse(240913) a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4
- Rat(66015) ADAM metallopeptidase with thrombospondin type 1 motif, 4
- domestic cat(101089488) ADAM metallopeptidase with thrombospondin type 1 motif, 4
- Horse(100033914) ADAM metallopeptidase with thrombospondin type 1 motif, 4
- dog(488651) ADAM metallopeptidase with thrombospondin type 1 motif, 4
- sheep(101106565) ADAM metallopeptidase with thrombospondin type 1 motif, 4
- cow(286806) ADAM metallopeptidase with thrombospondin type 1 motif, 4
- naked mole-rat(101702362) ADAM metallopeptidase with thrombospondin type 1 motif, 4
- domestic guinea pig(100712995) ADAM metallopeptidase with thrombospondin type 1 motif, 4
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ELISA
货号
说明
物种
Antibodies
货号
说明
物种反应性
应用
Anti-ADAMTS4, affinity isolated antibody,
物种反应性
bovine, guinea pig, horse, human, mouse, rat
应用
immunohistochemistry
western blot
western blot
Anti-ADAMTS4 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
Anti-ADAMTS4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-ADAMTS4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Monoclonal Anti-ADAMTS4 antibody produced in mouse, clone 2A6, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunoprecipitation (IP)
immunoprecipitation (IP)
Proteins
货号
说明
物种
ADAMTS-4, recombinant, His Tagged, This His Tagged Recombinant ADAMTS4 is used to study the degradation of extracellular matrix proteoglycans, to screen for inhibitors of proteoglycan hydrolysis and to characterize inhibitor actions.,
物种
human