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Merck
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The dorsal posterior insula subserves a fundamental role in human pain.

Nature neuroscience (2015-03-10)
Andrew R Segerdahl, Melvin Mezue, Thomas W Okell, John T Farrar, Irene Tracey
摘要

Several brain regions have been implicated in human painful experiences, but none have been proven to be specific to pain. We exploited arterial spin-labeling quantitative perfusion imaging and a newly developed procedure to identify a specific role for the dorsal posterior insula (dpIns) in pain. Tract tracing studies in animals identify a similar region as fundamental to nociception, which suggests the dpIns is its human homolog and, as such, a potential therapeutic target.

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辣椒素, from Capsicum sp., ≥50% (HPLC)