- Silver(I)-catalyzed deprotection of p-methoxybenzyl ethers: a mild and chemoselective method.
Silver(I)-catalyzed deprotection of p-methoxybenzyl ethers: a mild and chemoselective method.
The Journal of organic chemistry (2012-09-26)
Nicolas Kern, Thomas Dombray, Aurélien Blanc, Jean-Marc Weibel, Patrick Pale
PMID23002789
摘要
The p-methoxybenzyl protecting group (PMB) on various alcohols and an acid was efficiently and selectively cleaved by the action of a catalytic amount of silver(I) hexafluoroantimonate combined with 0.5 equiv of 1,3,5-trimethoxybenzene in dichloromethane at 40 °C.
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