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  • One-pot, Pd-catalyzed synthesis of trans-dihydrobenzofurans from o-aminophenols.

One-pot, Pd-catalyzed synthesis of trans-dihydrobenzofurans from o-aminophenols.

Organic letters (2010-03-27)
Ericsson D Coy, Ljubisa Jovanovic, Michael Sefkow
摘要

An efficient and facile synthesis of trans-dihydrobenzofurans has been accomplished from o-aminophenols and phenylpropenes via a novel (one-pot) diastereoselective Pd-catalyzed oxyarylation reaction. The development and optimization of this method is described.

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Sigma-Aldrich
2-氨基苯酚, 99%