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  • Direct dehydrative cross-coupling of tautomerizable heterocycles with alkynes via Pd/Cu-catalyzed phosphonium coupling.

Direct dehydrative cross-coupling of tautomerizable heterocycles with alkynes via Pd/Cu-catalyzed phosphonium coupling.

Chemical communications (Cambridge, England) (2010-05-08)
Fu-An Kang, James C Lanter, Chaozhong Cai, Zhihua Sui, William V Murray
摘要

The first chemoselective direct dehydrative cross-coupling of tautomerizable heterocycles with alkynes has been achieved via C-H/C-OH bond activations with direct C(sp(2))-C(sp) bond formation, which is in line with ideal synthesis using readily available materials.

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2-羟基喹喔啉, 99% (HPLC)