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Merck
CN
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主要文件

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安全信息

V900919

Sigma-Aldrich

两性霉素B 来源于链霉菌 属

suitable for cell culture, Vetec™, BioReagent

别名:

两性霉素B 来源于链霉菌 属, Fungizone

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About This Item

经验公式（希尔记法）:
C47H73NO17
CAS号:
1397-89-3
分子量:
924.08
Beilstein:
78342
EC 号:
215-742-2
MDL编号:
MFCD00877763
UNSPSC代码:
12352207
PubChem化学物质编号:
329830225

产品名称

两性霉素B 来源于链霉菌 属, Vetec™, reagent grade, BioReagent, suitable for cell culture, ~80%

等级

reagent grade

质量水平

100

产品线

BioReagent
Vetec™

方案

~80%

技术

cell culture | mammalian: suitable

抗生素抗菌谱

fungi
yeast

作用机制

cell membrane | interferes

储存温度

2-8°C

SMILES字符串

C[C@H]1O[C@@H](O[C@@H]2C[C@@H]3O[C@](O)(C[C@@H](O)C[C@@H](O)[C@H](O)CC[C@@H](O)C[C@@H](O)CC(=O)O[C@@H](C)[C@H](C)[C@H](O)[C@@H](C)\C=C\C=C\C=C\C=C\C=C\C=C\C=C\2)C[C@H](O)[C@H]3C(O)=O)[C@@H](O)[C@@H](N)[C@@H]1O

InChI

1S/C47H73NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-33(51)22-36(53)35(52)20-19-31(49)21-32(50)23-39(55)62-29(3)28(2)42(27)56/h5-18,27-38,40-44,46,49-54,56-58,61H,19-26,48H2,1-4H3,(H,59,60)/b6-5+,9-7+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28-,29-,30+,31+,32+,33-,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+/m0/s1

InChI key

APKFDSVGJQXUKY-INPOYWNPSA-N

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相关类别

生化/生理作用

两性霉素B可与甾醇结合，在膜中形成孔，并导致小分子的泄漏。该产品对真菌和酵母最有效。
两性霉素B可用于急性侵袭性真菌感染的初级治疗，例如曲霉菌病。

法律信息

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

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象形图

Health hazard
GHS08

警示用语：

Danger

危险声明

H372

危险分类

STOT RE 1

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

涉药品监管产品

从最新的版本中选择一种：

分析证书(COA)

Lot/Batch Number
WXBF2891V
WXBD6493V
WXBD0792V
WXBC6509V
WXBC4565V

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Randomized, double-blind clinical trial of amphotericin B colloidal dispersion vs. amphotericin B in the empirical treatment of fever and neutropenia.
White MH, et al.
Clinical Infectious Diseases, 27(2), 296-302 (1998)
Voriconazole versus amphotericin B for primary therapy of invasive aspergillosis.
Herbrecht R, et al.
The New England Journal of Medicine, 347(6), 408-415 (2002)
Malav S Trivedi et al.
The Journal of nutritional biochemistry, 25(10), 1011-1018 (2014-07-16)
Dietary interventions like gluten-free and casein-free diets have been reported to improve intestinal, autoimmune and neurological symptoms in patients with a variety of conditions; however, the underlying mechanism of benefit for such diets remains unclear. Epigenetic programming, including CpG methylation
Chitralekha Mohanty et al.
Anticancer research, 34(6), 2801-2806 (2014-06-13)
The use of ion radiation therapy is growing due to the continuously increasing positive clinical experience obtained. Therefore, there is a high interest in radio-biological experiments comparing the relative efficiency in cell killing of ions and photons as photons are
Rujiu Hu et al.
Journal of animal science and biotechnology, 12(1), 25-25 (2021-02-18)
Lactobacillus reuteri strains are widely used as probiotics to prevent and treat inflammatory bowel disease by modulating the host's immune system. However, the underlying mechanisms by which they communicate with the host have not been clearly understood. Bacterial extracellular vesicles
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