推荐产品
等级
reagent grade
产品线
Vetec™
检测方案
98%
mp
128-132 °C (lit.)
SMILES字符串
CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
InChI
1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1
InChI key
RJKFOVLPORLFTN-LEKSSAKUSA-N
基因信息
human ... PGR(5241)
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生化/生理作用
孕酮是维持妊娠的激素。它对几乎所有哺乳动物的胚胎形成、发育和存活都是必不可少的。这种激素通过孕激素受体发挥作用,孕激素受体在整个妊娠期特异表达于子宫内膜间质。已知它通过肌肉注射给药可预防早产。
诱导子宫内皮细胞的成熟和分泌活性;抑制排卵。 孕激素与乳腺癌发病有关。
其他说明
黄体分泌的类固醇激素。
法律信息
Vetec is a trademark of Merck KGaA, Darmstadt, Germany
警示用语:
Danger
危险声明
危险分类
Carc. 2 - Lact. - Repr. 1A
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Prophylactic administration of progesterone by vaginal suppository to reduce the incidence of spontaneous preterm birth in women at increased risk: a randomized placebo-controlled double-blind study.
American Journal of Obstetrics and Gynecology, 188(2), 419-424 (2003)
Biology of progesterone action during pregnancy recognition and maintenance of pregnancy.
Frontiers in Bioscience, 7(1-3), d1879-d1898 (2002)
NeuroImage, 118, 154-162 (2015-06-10)
Hippocampal volume has been shown to be sensitive to variations in estrogen and progesterone levels across rodents' estrous cycle. However, little is known about the covariation of hormone levels and brain structure in the course of the human menstrual cycle.
Nature reviews. Cancer, 13(6), 385-396 (2013-05-25)
Understanding the biology of the breast and how ovarian hormones impinge on it is key to rational new approaches in breast cancer prevention and therapy. Because of the success of selective oestrogen receptor modulators (SERMs), such as tamoxifen, and aromatase
The Journal of infectious diseases, 211(1), 10-18 (2014-07-18)
Protease inhibitor (PI)-based combination antiretroviral therapy (cART) is administered during pregnancy to prevent perinatal human immunodeficiency virus (HIV) transmission. However, PI use has been associated with adverse birth outcomes, including preterm delivery and small-for-gestational-age (SGA) births. The mechanisms underlying these
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