V900576
1,8-二羟基蒽醌
Vetec™, reagent grade, 96%
别名:
丹蒽醌, 二羟蒽醌
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关于此项目
经验公式（希尔记法）:
C14H8O4
化学文摘社编号:
分子量:
240.21
EC Number:
204-173-5
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
2054727
MDL number:
Assay:
96%
InChI key
QBPFLULOKWLNNW-UHFFFAOYSA-N
InChI
1S/C14H8O4/c15-9-5-1-3-7-11(9)14(18)12-8(13(7)17)4-2-6-10(12)16/h1-6,15-16H
SMILES string
Oc1cccc2C(=O)c3cccc(O)c3C(=O)c12
grade
reagent grade
product line
Vetec™
assay
96%
Gene Information
human ... RXRA(6256)
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Legal Information
Vetec is a trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
No data available
flash_point_c
No data available
Yong-Soo Kwon et al.
Biological & pharmaceutical bulletin, 27(5), 723-726 (2004-05-11)
Oxidative stress caused by an elevation in reactive oxygen species (ROS) plays an important role in Alzheimer's disease and other neurodegenerative diseases. In this study, we examined the neuroprotective effect of danthron (1,8-dihydroxyanthraquinone) against neurotoxicities induced by beta-amyloid (25-35), excitotoxins
Jo-Hua Chiang et al.
Chemical research in toxicology, 24(1), 20-29 (2010-12-04)
Anthraquinones have been shown to induce apoptosis in different types of tumor cells, but the mechanisms of danthron-induced cytotoxicity and apoptosis in human gastric cancer cells have not been adequately explored. This study investigated the roles of caspase cascades, ROS
Haitao Zhang et al.
The Journal of biological chemistry, 286(3), 1868-1875 (2010-11-19)
Retinoic X receptor (RXR) is a promising target for drug discovery against cancer and metabolic syndromes. Here, we identified a specific RXRα antagonist, danthron, from the traditional Chinese medicine rhubarb. Danthron repressed all tested RXRα-involved response element transcription, including the
Florian Pankewitz et al.
Journal of chemical ecology, 32(9), 2067-2072 (2006-07-13)
Eggs of several insect species are protected against natural enemies by noxious components. However, almost nothing is known about the fate of these defensive substances during egg development nor their site of biosynthesis. The eggs of several leaf beetle species
Chunyu Qiao et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 70(1), 136-143 (2007-09-11)
The interactions of fish sperm deoxyribonucleic acid (DNA) with anthraquinones, such as chrysophanol, physcion and 1,8-dihydroxy anthraquinone, were investigated by using ethidium bromide (EB) as fluorescence probe. The binding constants of anthraquinones and DNA were obtained by the fluorescence quenching
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