推荐产品
等级
pharmaceutical primary standard
API类
venlafaxine
制造商/商品名称
USP
应用
pharmaceutical (small molecule)
格式
neat
SMILES字符串
Cl[H].COc1ccc(cc1)C(CN(C)C)C2(O)CCCCC2
InChI
1S/C17H27NO2.ClH/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14;/h7-10,16,19H,4-6,11-13H2,1-3H3;1H
InChI key
QYRYFNHXARDNFZ-UHFFFAOYSA-N
基因信息
human ... SLC6A2(6530) , SLC6A4(6532)
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一般描述
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
应用
Venlafaxine hydrochloride USP reference standard intended for use in specified quality tests and assays.
Also used to prepare standard, system suitability, and standard stock solution for assay, impurity analysis, and performance test according to the given below monographs of United States Pharmacopeia (USP):
Also used to prepare standard, system suitability, and standard stock solution for assay, impurity analysis, and performance test according to the given below monographs of United States Pharmacopeia (USP):
- Venlafaxine Hydrochloride
- Venlafaxine Tablets
- Venlafaxine Hydrochloride Extended-Release Capsules
- Desvenlafaxine
生化/生理作用
文拉法辛是抗抑郁药。文拉法辛在人中的抗抑郁作用机制与其在中枢神经系统中神经递质活性的增强有关。文拉法辛是神经元 5-羟色胺和去甲肾上腺素再摄取的有效抑制剂，是多巴胺再摄取的弱抑制剂。在体外，文拉法辛对毒蕈碱、组胺能或 α-1 肾上腺素能受体无明显活性。文拉法辛不具有 MAO 抑制剂活性。
分析说明
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
其他说明
Sales restrictions may apply.
危险声明
预防措施声明
危险分类
Aquatic Chronic 2
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Desvenlafaxine
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 43(5), 1280-1280 (2020)
Venlafaxine Tablets
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 42(3), 4595-4595 (2017)
Venlafaxine Hydrochloride Extended-Release Capsules
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 4598-4598 (2022)
Venlafaxine Hydrochloride
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 40(1), 4597-4597 (2020)
R L Rudolph et al.
Journal of clinical psychopharmacology, 16(3 Suppl 2), 54S-59S (1996-06-01)
The tolerability and safety of venlafaxine hydrochloride, a new serotonin and norepinephrine reuptake inhibitor, are reviewed in this article. The data presented here are based on a pool of 3,082 patients who were treated with this agent during clinical trials.
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