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主要文件

安全信息

1673001

USP

Travoprost

United States Pharmacopeia (USP) Reference Standard

别名:

Travoprost solution

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About This Item

经验公式(希尔记法):
C26H35F3O6
分子量:
500.55
MDL编号:
UNSPSC代码:
41116107
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

travoprost

制造商/商品名称

USP

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

−20°C

SMILES字符串

FC(F)(F)c1cc(ccc1)OC[C@H](O)\C=C\[C@@H]2[C@H]([C@H](C[C@H]2O)O)C\C=C/CCCC(=O)OC(C)C

InChI

1S/C26H35F3O6/c1-17(2)35-25(33)11-6-4-3-5-10-21-22(24(32)15-23(21)31)13-12-19(30)16-34-20-9-7-8-18(14-20)26(27,28)29/h3,5,7-9,12-14,17,19,21-24,30-32H,4,6,10-11,15-16H2,1-2H3/b5-3-,13-12+/t19-,21-,22-,23+,24-/m1/s1

InChI key

MKPLKVHSHYCHOC-AHTXBMBWSA-N

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

应用

  • Innovative eye drop applications: Travoprost has been incorporated into engineered lipoprotein nanoparticles, showcasing a novel method for drug delivery aimed at enhancing therapeutic efficacy in ocular treatments, particularly for conditions like glaucoma and ocular hypertension (Fukuda et al., 2024).
  • Prostaglandin analogs in glaucoma treatment: The effectiveness and safety of benzalkonium chloride-preserved travoprost eye drops have been critically evaluated, providing insights into their impact on ocular health, particularly on conjunctival goblet cells, which are vital for maintaining eye surface health in glaucoma patients (Nagstrup, 2023).
  • Travoprost liquid nanocrystals: Research into travoprost liquid nanocrystals has demonstrated their potential as a significant advancement in glaucoma therapy, offering improved delivery mechanisms and potentially greater efficacy in reducing intraocular pressure (El-Gendy et al., 2023).
  • Cerebrospinal fluid reabsorption: Studies on prostaglandin analog effects on cerebrospinal fluid reabsorption via nasal mucosa reveal new roles for travoprost in physiological processes beyond ocular applications, indicating potential new therapeutic pathways (Pedler et al., 2021).

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

Sales restrictions may apply.

象形图

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警示用语:

Danger

危险声明

危险分类

Eye Irrit. 2 - Flam. Liq. 2

储存分类代码

3 - Flammable liquids

WGK

WGK 2

闪点(°F)

55.4 °F

闪点(°C)

13 °C

法规信息

监管及禁止进口产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Travoprost
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 32(4), 4469-4469 (2013)
Travoprost Ophthalmic Solution
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 46(2), 4471-4471 (2020)

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