推荐产品
等级
pharmaceutical primary standard
API类
thimerosal
制造商/商品名称
USP
mp
234-237 °C (dec.) (lit.)
应用
pharmaceutical (small molecule)
包装形式
neat
储存温度
2-8°C
SMILES字符串
[Na+].CC[Hg]Sc1ccccc1C([O-])=O
InChI
1S/C7H6O2S.C2H5.Hg.Na/c8-7(9)5-3-1-2-4-6(5)10;1-2;;/h1-4,10H,(H,8,9);1H2,2H3;;/q;;2*+1/p-2
InChI key
RTKIYNMVFMVABJ-UHFFFAOYSA-L
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一般描述
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
应用
Thimerosal USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Thimerosal Tincture
- Thimerosal Topical Aerosol®
- Thimerosal Topical Solution
生化/生理作用
硫柳汞是一种巯基（硫醇）氧化剂，能抑制多种巯基依赖性酶和蛋白质，如PI3激酶依赖性蛋氨酸合成酶、谷氨酸转运受体和Na++K+依赖性ATP酶。
分析说明
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
其他说明
Sales restrictions may apply.
法律信息
Aerosol is a registered trademark of Cytec Technology Corp.
免责声明
As part of the corporationglobal plan to support the Minamata Convention in eliminatingmercury-containing compounds, as of January 2021 customers will be required toprovide an End-Use Declaration. The sales of thimerosal will be restricted forapproved applications only, such as preservative in vaccine manufacturing,preservative in eye cosmetics, research use within academia (excludingpreservation intent) and as reference material only. The product is notintended for use as a biocide under global biocide regulations, including butnot limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act ,European Biocidal Products Regulation, Canada’s Pest Management RegulatoryAgency, Turkey’s Biocidal Products Regulation,Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR)and others.
For U.S. Customers: Contains mercury; Do not place in trash - dispose according to local, state, or federal laws.
警示用语：
Danger
危险分类
Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2 Oral
靶器官
Kidney
储存分类代码
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
非剧毒-急性毒性1
Thimerosal Topical Aerosol
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 4346-4346 (2018)
Thimerosal Topical Solution
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 4347-4347 (2013)
Thimerosal
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 40(5), 4344-4344 (2020)
Thimerosal Tincture
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 4348-4348 (2013)
David A Geier et al.
Biological trace element research, 163(1-2), 28-38 (2014-11-11)
Thimerosal is an organic mercury (Hg)-containing compound (49.55 % Hg by weight) historically added to many multi-dose vials of vaccine as a preservative. A hypothesis testing case-control study evaluated automated medical records in the Vaccine Safety Datalink (VSD) for organic Hg
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