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Merck
CN

1643260

USP

盐酸坦洛新 盐酸盐

United States Pharmacopeia (USP) Reference Standard

别名:

5-[(2R)-2-[[2-(2-Ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamide hydrochloride

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About This Item

经验公式(希尔记法):
C20H28N2O5S · HCl
分子量:
444.97
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

tamsulosin

制造商/商品名称

USP

应用

pharmaceutical (small molecule)

格式

neat

储存温度

2-8°C

SMILES字符串

Cl.CCOc1ccccc1OCCN[C@H](C)Cc2ccc(OC)c(c2)S(N)(=O)=O

InChI

1S/C20H28N2O5S.ClH/c1-4-26-17-7-5-6-8-18(17)27-12-11-22-15(2)13-16-9-10-19(25-3)20(14-16)28(21,23)24;/h5-10,14-15,22H,4,11-13H2,1-3H3,(H2,21,23,24);1H/t15-;/m1./s1

InChI key

ZZIZZTHXZRDOFM-XFULWGLBSA-N

基因信息

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Tamsulosin hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Tamsulosin Hydrochloride Capsules
  • Dutasteride and Tamsulosin Hydrochloride Capsules

生化/生理作用

Tamsulosin is an α1A/1D-adrenoceptor antagonist used as a treatment of benign prostatic hypertrophy (BPH). Its activity as an ? blocker also affects the iris, and has led to complications during cataract surgery, a condition called "floppy iris" syndrome.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

Sales restrictions may apply.

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


分析证书(COA)

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访问文档库

Tamsulosin Hydrochloride Capsules
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 46(3) (2022)
Dutasteride and Tamsulosin Hydrochloride Capsules
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 46(5) (2023)
Tamsulosin Hydrochloride
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 42(2), 4211-4211 (2020)
Shuo Yang et al.
The AAPS journal, 16(4), 860-871 (2014-05-31)
Multi-pellet formulations are advantageous for the controlled release of drugs over single-unit dosage forms. To understand the diffusion controlled drug release mechanism, the pellet structure and drug release from a single pellet (not at dose level) were studied using synchrotron
Nannan Chu et al.
Clinical therapeutics, 37(2), 462-472 (2014-12-04)
The primary aim of this study was to evaluate whether there was clinically significant pharmacokinetic (PK) interaction between finasteride and tamsulosin in healthy Chinese male subjects. This was an open-label, randomized, 3-period, crossover study. Subjects received single and multiple doses

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