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About This Item
经验公式（希尔记法）:
C23H27FN4O2
CAS号:
分子量:
410.48
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
等级
pharmaceutical primary standard
API类
risperidone
制造商/商品名称
USP
应用
pharmaceutical (small molecule)
格式
neat
SMILES字符串
CC1=C(CCN2CCC(CC2)c3noc4cc(F)ccc34)C(=O)N5CCCCC5=N1
InChI
1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3
InChI key
RAPZEAPATHNIPO-UHFFFAOYSA-N
基因信息
human ... DRD2(1813) , HTR2A(3356) , HTR2C(3358)
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一般描述
Risperidone is a new central 5-hydroxytryptamine2 and dopamine D2 antagonist. It is used to treat agitation, aggression,and psychosis caused during demnetia. It is a neuroleptic drug. It is also an atypical antipsychotic drug which is used for treating schizophrenia.
应用
It was used as reference standard during RP-UPLC analysis for determination of risperidone related compounds in Risperdal® Consta (risperidone long-acting injection).
分析说明
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
其他说明
Sales restrictions may apply.
法律信息
Risperdal is a registered trademark of Johnson & Johnson
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产品编号
说明
价格
警示用语：
Danger
危险声明
危险分类
Acute Tox. 3 Oral
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Development and Validation of RP-UPLC Method for Determination of Related Substances in Risperdal? Consta?.
Chen, Cheng-Tung, Cheng-Wei Cheng, and Yu-Fang Hu.
Journal of Chromatography and Separation Techniques, 6.6, 1-1 (2015)
Jérôme A J Becker et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 39(9), 2049-2060 (2014-03-13)
The etiology of Autism Spectrum Disorders (ASDs) remains largely unknown. Identifying vulnerability genes for autism represents a major challenge in the field and allows the development of animal models for translational research. Mice lacking the mu opioid receptor gene (Oprm1(-/-))
Christian Spang Pedersen et al.
Behavioural brain research, 273, 63-72 (2014-07-30)
Schizophrenia is a severe psychiatric disorder characterized by three symptom domains, positive (hallucinations, obsession), negative (social withdrawal, apathy, self-neglect) and cognitive (impairment in attention, memory and executive function). Whereas current medication ameliorates positive symptomatology, negative symptoms as well as cognitive
Katherine Seto et al.
Therapeutic drug monitoring, 33(3), 275-283 (2011-03-26)
Although risperidone is commonly used in the acute and maintenance treatment of schizophrenia, the role of therapeutic drug monitoring has yet to be elucidated. The purpose of this review was to determine whether risperidone warrants therapeutic drug monitoring in patients
A comparison of risperidone and haloperidol for the prevention of relapse in patients with schizophrenia.
Csernansky JG
The New England Journal of Medicine, 346(1), 16-22 (2002)
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