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Merck
CN

1604610

USP

Risedronate sodium

United States Pharmacopeia (USP) Reference Standard

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别名:
Risedronic acid monosodium salt hemi(pentahydrate)
经验公式(希尔记法):
C7H10NNaO7P2 · 2.5H2O
分子量:
350.13
MDL编号:
UNSPSC代码:
41116107
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

risedronate

制造商/商品名称

USP

应用

pharmaceutical (small molecule)

格式

neat

SMILES字符串

OP(C(P(O)([O-])=O)(O)CC1=CC=CN=C1)(O)=O.[Na+]

InChI

1S/2C7H11NO7P2.2Na.5H2O/c2*9-7(16(10,11)12,17(13,14)15)4-6-2-1-3-8-5-6;;;;;;;/h2*1-3,5,9H,4H2,(H2,10,11,12)(H2,13,14,15);;;5*1H2/q;;2*+1;;;;;/p-2

InChI key

HYFDYHPNTXOPPO-UHFFFAOYSA-L

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一般描述

Risedronate sodium is a member of the pyridinyl class of bisphosphonates. It is mostly used as an antiresorptive agent. It can be used in treating and preventing postmenopausal and glucocorticoid-induced osteoporosis.

应用

Risedronate sodium USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

Sales restrictions may apply.

象形图

Health hazardExclamation mark

警示用语:

Warning

危险分类

Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - STOT SE 2

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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CUNHA F.
American Journal of Surgery, 76(3), 244-260 (1948)
Eliska Vaculikova et al.
Molecules (Basel, Switzerland), 19(11), 17848-17861 (2014-11-07)
One approach for the enhancement of oral drug bioavailability is the technique of nanoparticle preparation. Risedronate sodium (Biopharmaceutical Classification System Class III) was chosen as a model compound with high water solubility and low intestinal permeability. Eighteen samples of risedronate
Yoshihisa Hirota et al.
PloS one, 10(4), e0125737-e0125737 (2015-04-16)
UbiA prenyltransferase domain-containing protein 1 (UBIAD1) plays a significant role in vitamin K2 (MK-4) synthesis. We investigated the enzymological properties of UBIAD1 using microsomal fractions from Sf9 cells expressing UBIAD1 by analysing MK-4 biosynthetic activity. With regard to UBIAD1 enzyme
Jin Woo Park et al.
Archives of pharmacal research, 37(12), 1560-1569 (2013-11-21)
Risedronate is widely used clinically to treat osteoporosis, Paget's disease, hypercalcemia, bone metastasis, and multiple myeloma. However, its oral efficacy is restricted due to its low bioavailability and severe gastrointestinal adverse effects. This study was designed to evaluate the effect

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