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Merck
CN

1502508

USP

青霉素G钾

United States Pharmacopeia (USP) Reference Standard

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别名:
青霉素G 钾盐, 苄青霉素 钾盐
经验公式(希尔记法):
C16H17KN2O4S
CAS号:
分子量:
372.48
Beilstein:
3832841
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

penicillin & derivatives

制造商/商品名称

USP

应用

pharmaceutical (small molecule)

格式

neat

SMILES字符串

[K+].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)Cc3ccccc3)C([O-])=O

InChI

1S/C16H18N2O4S.K/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/q;+1/p-1/t11-,12+,14-;/m1./s1

InChI key

IYNDLOXRXUOGIU-LQDWTQKMSA-M

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一般描述

Penicillin G is a β-lactam antibiotic having antimicrobial action against Gram-positive and Gram-negative bacteria. Penicillin G potassium USP reference standard is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Penicillin G potassium USP Reference standard for use in specified quality tests and assays.
Penicillin G potassium USP reference standard is used to prepare standard solutions for identification and test system suitability.(1) Further information is available in monograph, Penicillin G Potassium, USP43-NF38 – 3436 of United States Pharmacopeia (USP).

生化/生理作用

作用机制:青霉素G通过与青霉素结合蛋白(PBP)结合抑制肽聚糖链交联,从而抑制细胞壁合成。

抗菌谱:本品具有抗革兰氏阳性菌和革兰氏阴性菌活性。

其他说明

This product is part of the USP Biologics program.
Sales restrictions may apply.

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象形图

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警示用语:

Warning

危险声明

预防措施声明

危险分类

Skin Sens. 1

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

分析证书(COA)

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访问文档库

Penicillin G Potassium
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 41(3), 3436-3436 (2020)
Matthieu Picard et al.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 113(1), 75-81 (2014-05-27)
The absence of commercially available penicilloyl-polylysine (PPL) for most of the last decade severely hampered the practice of penicillin allergy evaluation because skin testing without PPL is reported to have a poor negative predictive value (NPV). To determine the safety
Nahid Pourreza et al.
Journal of AOAC International, 97(4), 1225-1229 (2014-08-26)
A cloud point extraction (CPE) method for determination of trace amounts of penicillin G by spectrophotometry based on its effect on the triiodide ion (I3(-)) has been developed. Penicillin G is converted to the corresponding penicilloic acid by carrying out
Chronic inflammatory demyelinating polyneuropathy associated with neurosyphilis.
Evangelia Kararizou et al.
The American journal of the medical sciences, 349(1), 90-91 (2014-12-04)

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