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1491300

USP

催产素

United States Pharmacopeia (USP) Reference Standard

别名:

垂体后叶提取物, α-多巴胺, 催产激素

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关于此项目

经验公式（希尔记法）:
C43H66N12O12S2
化学文摘社编号:
50-56-6
分子量:
1007.19
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329750651
MDL number:
MFCD00076731
Beilstein/REAXYS Number:
3586108
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grade

pharmaceutical primary standard

API family

oxytocin

form

powder

manufacturer/tradename

USP

application(s)

USP Biologics
pharmaceutical (small molecule)

format

neat

SMILES string

[H]N[C@H]1CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)[C@@H](C)CC)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CC(C)C)C(=O)NCC(N)=O

InChI

1S/C43H66N12O12S2/c1-5-22(4)35-42(66)49-26(12-13-32(45)57)38(62)51-29(17-33(46)58)39(63)53-30(20-69-68-19-25(44)36(60)50-28(40(64)54-35)16-23-8-10-24(56)11-9-23)43(67)55-14-6-7-31(55)41(65)52-27(15-21(2)3)37(61)48-18-34(47)59/h8-11,21-22,25-31,35,56H,5-7,12-20,44H2,1-4H3,(H2,45,57)(H2,46,58)(H2,47,59)(H,48,61)(H,49,66)(H,50,60)(H,51,62)(H,52,65)(H,53,63)(H,54,64)/t22-,25-,26-,27-,28-,29-,30-,31-,35-/m0/s1

InChI key

XNOPRXBHLZRZKH-DSZYJQQASA-N

Gene Information

human ... OXTR(5021)

General description

Oxytocin is a nonapeptide hormone produced in the hypothalamus and secreted by the posterior pituitary. It stimulates uterine contractions and lactation. The USP reference standard enables bioassay validation, potency testing, and structural identity confirmation in oxytocin products.

The USP biologics peptides category encompasses a diverse range of therapeutic peptides that are essential in managing various medical conditions. These peptides, typically consisting of amino acid sequences of 40 residues or less, are critical for the development of high-quality medicines. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of peptide therapeutics throughout their lifecycle.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

Application

催产素USP参考标准品，预期用途是USP规定的指定质量测试和检测。也用于USP各论，例如：
  • 催产素注射液

Biochem/physiol Actions

刺激子宫收缩和哺乳；增加Na+ 排泄；刺激子宫肌层GTP酶和磷脂酶 C。

Analysis Note

这些产品仅供测试和分析使用。它们不适用于人类或动物的给药，不可用于诊断、治疗或治愈任何疾病。

Other Notes

可能适用相应的销售限制。
该产品是美国药典生物制品计划的一部分。

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存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

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Oxytocin
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 34(3), 3366-3366 (2013)
Elliot C Brown et al.
Psychiatry research, 219(3), 436-442 (2014-07-23)
Patients with schizophrenia suffer from dysfunctional social behaviour. Social approach and avoidance (AA) has been associated with motor responses, as the affective valence and gaze direction of facial stimuli can bias push and pull motor tendencies. The aim of this
Mikko J Peltola et al.
Emotion (Washington, D.C.), 14(3), 469-477 (2014-04-23)
Recent studies suggest that parental caregiving is associated with adaptive changes in neurocognitive responses to emotional cues and oxytocin function, possibly reflecting the increased need of parents to monitor infants' emotional states. In the current study, we investigated whether the
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全球贸易项目编号

货号GTIN
1491300-1VL04061838626110