1475008
USP
新霉素
United States Pharmacopeia (USP) Reference Standard
别名:
Benzamide, N-[7-[[3-O-(aminocarbonyl)-6-deoxy-5-C-methyl-4-O-methyl-ß-l-lyxohexopyranosyl]oxy]-4-hydroxy-8-methyl-2-oxo-2H-1-benzopyran-3-yl]-4-hydroxy-3-
(3-methyl-2-butenyl), monohydrate, Streptonivicin
About This Item
推荐产品
等级
pharmaceutical primary standard
API类
novobiocin
制造商/商品名称
USP
应用
pharmaceutical (small molecule)
包装形式
neat
储存温度
−20°C
SMILES字符串
[Na+].N([C-]2C(=O)Oc3c(ccc(c3C)OC4OC(C(C(C4O)OC(=O)N)OC)(C)C)C2=O)C(=O)c1cc(c(cc1)O)CC=C(C)C
InChI
1S/C31H35N2O11.Na/c1-14(2)7-8-16-13-17(9-11-19(16)34)27(37)33-21-22(35)18-10-12-20(15(3)24(18)42-28(21)38)41-29-23(36)25(43-30(32)39)26(40-6)31(4,5)44-29;/h7,9-13,23,25-26,29,34,36H,8H2,1-6H3,(H2,32,39)(H,33,37);/q-1;+1
InChI key
AXOUUAINTJNFRS-UHFFFAOYSA-N
一般描述
For further information and support please go to the website of the issuing Pharmacopoeia.
应用
- Enhancing antibiotic effectiveness: Novobiocin is explored as a co-agent in antibacterial strategies, particularly in enhancing the efficacy of other antibiotics like rifampicin against multidrug-resistant bacteria. This underscores its role in combating bacterial resistance and its potential application in developing new antibacterial therapies (Ramirez et al., 2024).
- Gene expression modulation: The study investigates novobiocin′s impact on gene expression related to antibiotic production, demonstrating its utility in biotechnological applications to boost the yield of other clinically important antibiotics. This research highlights its role in understanding and manipulating microbial pathways for enhanced drug production (Zhukrovska et al., 2024).
- Microbial metabolism in animal health: Novobiocin′s effects on microbial nitrogen metabolism in composted poultry litter are assessed, providing insights into its environmental and veterinary applications. This study illustrates its broader applications beyond human medicine, particularly in agricultural and environmental health (Arzola-Alvarez et al., 2022).
分析说明
其他说明
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral - Skin Sens. 1
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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