等级
pharmaceutical primary standard
API类
nitrofurantoin
制造商/商品名称
USP
应用
pharmaceutical (small molecule)
格式
neat
SMILES字符串
[O-][N+](=O)c1ccc(\C=N\N2CC(=O)NC2=O)o1
InChI
1S/C8H6N4O5/c13-6-4-11(8(14)10-6)9-3-5-1-2-7(17-5)12(15)16/h1-3H,4H2,(H,10,13,14)/b9-3+
InChI key
NXFQHRVNIOXGAQ-YCRREMRBSA-N
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一般描述
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
分析说明
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
其他说明
Sales restrictions may apply.
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产品编号
说明
价格
警示用语：
Danger
危险声明
危险分类
Acute Tox. 4 Oral - Resp. Sens. 1 - Skin Sens. 1
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
K A Boggess et al.
Obstetrical & gynecological survey, 51(6), 367-370 (1996-06-01)
Acute pulmonary reactions to nitrofurantoin are an uncommon side effect of therapy and can cause minor or life-threatening pulmonary dysfunction. Symptoms include fever, chills, cough, pleuritic chest pain, dyspnea. Rarely, pleural effusion and/or pulmonary hemorrhage may occur. Diagnosis is made
Reappraisal of the risk/benefit of nitrofurantoin: review of toxicity and efficacy.
R R Shah et al.
Adverse drug reactions and acute poisoning reviews, 8(4), 183-201 (1989-01-01)
C M Witten
Archives of physical medicine and rehabilitation, 70(1), 55-57 (1989-01-01)
Nitrofurantoin is frequently used by the physiatrist for treatment of urinary tract infections or for urinary antimicrobial prophylaxis. There is a substantial risk of acute and chronic pulmonary side effects with this medication. The acute pulmonary toxicity presents with fever
H Thoumsin et al.
Infection, 18 Suppl 2, S94-S97 (1990-01-01)
Pregnancy induces anatomical and physiological changes in the urinary tract. In this condition a bacteriuria, even asymptomatic, may lead more frequently to pyelonephritis. Asymptomatic bacteriuria in pregnant women has therefore got to be treated. According to recent studies, long course
Nitrofurantoin toxicity in children.
M J Coraggio et al.
The Pediatric infectious disease journal, 8(3), 163-166 (1989-03-01)
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