等级
pharmaceutical primary standard
API类
neomycin
制造商/商品名称
USP
应用
pharmaceutical (small molecule)
格式
neat
InChI
1S/C23H46N6O13.H2O4S/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22;1-5(2,3)4/h5-23,30-36H,1-4,24-29H2;(H2,1,2,3,4)/t5-,6+,7-,8+,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22?,23+;/m1./s1
InChI key
OIXVKQDWLFHVGR-GQTDVWSESA-N
一般描述
Neomycin Sulfate is the sulfate salt of a kind of neomycin, an antibacterial substance produced by the growth of Streptomyces fradiae Waksman (Fam. Streptomycetaceae), or a mixture of two or more such salts, the main component being neomycin B sulfate. It has a potency equivalent to NLT 600 µg of neomycin/mg, calculated on the dried basis.
Neomycin sulfate USP reference standard is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets, has been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Neomycin sulfate USP reference standard is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets, has been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
应用
Neomycin sulfate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Neomycin Sulfate Tablets
- Neomycin Sulfate Cream
- Neomycin Sulfate Ointment
- Neomycin Sulfate Ophthalmic Ointment
- Neomycin Sulfate Oral Solution
- Neomycin Sulfate and Hydrocortisone Cream
注意
Stock solutions should be filter sterilized and stored at 2-8°C, and are stable at 37°C for 5 days. A 1 mg/mL neomycin solution in .1 M phosphate buffer, pH 8.0 should be used within 14 days when stored at 0-5°C. Solutions should be protected from light or moisture.
制备说明
Neomycin sulfate is soluble in H2O at 50 mg/mL, yielding a clear solution.
其他说明
This product is part of the USP Biologics program.
法律信息
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
警示用语:
Danger
危险声明
危险分类
Resp. Sens. 1 - Skin Sens. 1
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
监管及禁止进口产品
Neomycin and Polymyxin B Sulfates, Bacitracin Zinc, and Lidocaine Ointment
United States Pharmacopeia, 28(4) (2013)
Neomycin Sulfate and Hydrocortisone Otic Suspension
United States Pharmacopeia, 49(5) (2013)
Neomycin Sulfate
United States Pharmacopeia, 48(1) (2023)
Neomycin and Polymyxin B Sulfates Ophthalmic Ointment
United States Pharmacopeia, 39(5), 3114-3114 (2017)
Neomycin and Polymyxin B Sulfates and Hydrocortisone Ophthalmic Suspension
United States Pharmacopeia, 3123-3123 (2013)
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