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Merck
CN
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主要文件

安全信息

1453049

USP

Naloxone Related Compound D CII

United States Pharmacopeia (USP) Reference Standard

别名:

(4R, 4aS, 7aR, 12bS)-3-allyl-4a,9-dihydroxy-2,3,4,4a-tetrahydro-1H,4,12- methanobenzofuro[3,2-e]-isoquinolin-7(7aH)-one

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About This Item

经验公式(希尔记法):
C19H19NO4
CAS号:
分子量:
325.36
MDL编号:
UNSPSC代码:
41116107
NACRES:
NA.24

一般描述

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

应用


  • Interactive effects of opioid and adrenergic-α2 receptor agonists: Research highlights the complex interactions between µ-opioid and adrenergic-α2 receptor agonists in rats, focusing on the primary Kratom alkaloid Mitragynine and its metabolite 7-Hydroxymitragynine. This study is pivotal for understanding the biochemical pathways involved in opioid receptor antagonist research, offering insights into naloxone-related compound applications in opioid addiction and withdrawal management (Hiranita et al., 2022).

  • Diels-Alder reactions of morphinan derivatives: The synthesis and transformations of Diels-Alder adducts of morphinan-6,8-dienes are discussed, illuminating the role of naloxone analogs in synthesizing novel opioid receptor antagonists. These findings contribute to the opioid antagonist research, particularly in exploring structural analogs of naloxone for enhanced therapeutic effects (Marton et al., 2022).

  • Impact of brain metastases on methylnaltrexone: A post hoc analysis of three randomized studies investigates the influence of brain metastases on the CNS effects of methylnaltrexone. This research underlines the importance of naloxone derivatives in modifying opioid-induced side effects, which is crucial for the development of safer opioid antagonists in supportive cancer care (Brenner et al., 2021).

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  

其他说明

Sales restrictions may apply.

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Warning

危险声明

危险分类

Acute Tox. 4 Oral

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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