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主要文件

1440808

USP

Metoclopramide hydrochloride

United States Pharmacopeia (USP) Reference Standard

别名:

甲氧氯普胺 单盐酸盐 一水合物

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About This Item

经验公式(希尔记法):
C14H22ClN3O2 · HCl · H2O
CAS号:
分子量:
354.27
MDL编号:
UNSPSC代码:
41116107
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

metoclopramide

制造商/商品名称

USP

应用

pharmaceutical (small molecule)

包装形式

neat

SMILES字符串

[Cl-].Clc1c(cc(c(c1)C(=O)NCCN(CC)CC)OC)N.O.[H+]

InChI

1S/C14H22ClN3O2.ClH.H2O/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3;;/h8-9H,4-7,16H2,1-3H3,(H,17,19);1H;1H2

InChI key

KJBLQGHJOCAOJP-UHFFFAOYSA-N

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Metoclopramide hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:
  • Metoclopramide Tablets
  • Metoclopramide Oral Solution
  • Metoclopramide Injection
  • Prazosin Hydrochloride

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

Sales restrictions may apply.

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警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Allen Lee
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 17(9), 1553-1556 (2013-06-27)
Gastroparesis is a chronic motility disorder that leads to delayed gastric emptying and negatively impacts morbidity, mortality, and quality of life. This paper provides an overview of the pathophysiology leading to symptoms in gastroparesis, discusses tests for diagnosis, and examines
Moshe Yair Kasirer et al.
American journal of physiology. Gastrointestinal and liver physiology, 306(5), G439-G444 (2014-01-11)
Feeding intolerance resulting from delayed gastric emptying is common in premature neonates. Metoclopramide (MCP), the most frequently used prokinetic drug in neonates, enhances gastric muscle contractility through inhibition of dopamine receptors. Although its therapeutic benefit is established in adults, limited
Z Eras et al.
European review for medical and pharmacological sciences, 17(12), 1655-1657 (2013-07-09)
Gastroesophageal reflux disease (GERD) may occur with poor weight gain, esophagitis, hematemesis and respiratory problems in an infant. Common treatment strategies include positioning, feeding thickeness, histamine2 receptor antagonists, antiacids, and prokinetics. Metoclopramide is a prokinetic drug used to treat GERD
Xiong Wang et al.
African journal of traditional, complementary, and alternative medicines : AJTCAM, 10(4), 24-35 (2013-10-23)
The study investigated the pharmacodynamism and mechanism of Chinese medicinal formula-Huiru Yizeng Yihao (NO.1 HRYZ) on the model rats of hyperpro-lactinemia and the model rats of hyperplasia of mammary gland (HMG), and studied the internal connection between hyperprolactinemia and HMG..
Anastasios Koulaouzidis et al.
Current medical research and opinion, 29(9), 1171-1185 (2013-06-25)
The use of purging for bowel cleansing prior to small-bowel capsule endoscopy (SBCE) has now been established in clinical practice. Despite that, the number of incomplete SBCEs is still around 15-20%. To date, the use of prokinetics in SBCE -

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