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Merck
CN
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主要文件

1411038

USP

Methimazole Related Compound C

United States Pharmacopeia (USP) Reference Standard

别名:

1-Methyl-2-(methylthio)-1H-imidazole, 1-Methyl-2-(methylsulphanyl)-1H-imidazole

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About This Item

经验公式（希尔记法）:
C5H8N2S
CAS号:
14486-52-3
分子量:
128.20
MDL编号:
MFCD25959069
UNSPSC代码:
41116107
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

methimazole

制造商/商品名称

USP

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-8°C

SMILES字符串

S(C)c1[n](ccn1)C

InChI

1S/C5H8N2S/c1-7-4-3-6-5(7)8-2/h3-4H,1-2H3

InChI key

LKIVEIAXFZBGMO-UHFFFAOYSA-N

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相关类别

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

应用


  • Nephrotoxicity Studies in Renal Cells: Methimazole Related Compound C was used in a study to explore the role of biotransformation and oxidative stress in 3,5-dichloroaniline-induced nephrotoxicity. This research provides insights into the cellular mechanisms affected by Methimazole and its related compounds(Racine et al., 2016).


  • Phenytoin Teratogenicity Research: Investigations into the bioactivation of phenytoin, involving lipoxygenase-catalyzed reactions that may be relevant to Methimazole Related Compound C, provide critical data on the enzymatic pathways that contribute to drug-induced teratogenic effects. This research assists in the development of safer pharmaceuticals by identifying hazardous metabolites (Yu and Wells, 1995).


  • Enzyme Inhibition Studies: The impact of thionamides and related compounds on enzyme activities was studied, highlighting how Methimazole Related Compound C affects important metabolic enzymes like trimethylamine oxidase. This is essential for developing medications that minimize adverse effects on metabolic processes (Pearson et al., 1982).


分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

Sales restrictions may apply.

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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