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Merck
CN

1379401

USP

美洛昔康

United States Pharmacopeia (USP) Reference Standard

别名:

4-羟基-2-甲基- N -(5-甲基-2-噻唑基)-2 H -1,2-苯并噻嗪-3-甲酰胺 1,1-二氧化物

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关于此项目

经验公式(希尔记法):
C14H13N3O4S2
化学文摘社编号:
分子量:
351.40
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24
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产品名称

美洛昔康, United States Pharmacopeia (USP) Reference Standard

InChI

1S/C14H13N3O4S2/c1-8-7-15-14(22-8)16-13(19)11-12(18)9-5-3-4-6-10(9)23(20,21)17(11)2/h3-7,19H,1-2H3,(H,15,16)/b13-11+

InChI key

DWMREKMVXIFPFM-ACCUITESSA-N

grade

pharmaceutical primary standard

API family

meloxicam

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

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Other Notes

可能适用相应的销售限制。

Analysis Note

这些产品仅供测试和化验使用。它们不适用于人类或动物,也不能用于诊断、治疗或治愈任何类型的疾病。

Application

美洛昔康USP参标准品,预期用途是USP规定的指定质量测试和检测。也用于USP各论,例如:
  • 美洛昔康口服混悬液
  • 美洛昔康片

General description

本产品按照发行药典的发行和规定提供。支持本产品的所有信息,包括安全数据表和任何产品信息传单,都是在发行药典的授权下开发和发布的。如需进一步信息和支持,请访问现行药典网站。

pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Brian J Gates et al.
Expert opinion on pharmacotherapy, 6(12), 2117-2140 (2005-10-04)
The discovery of two distinct isoenzymes of COX has led to the development and clinical introduction of COX-2 inhibitors with increased selectivity onto the market. Meloxicam is a non-steroidal anti-inflammatory drug (NSAID) of the oxicam class, and is a preferential
Meloxicam--a safer NSAID?
Drug and therapeutics bulletin, 36(8), 62-64 (1999-01-07)
Shunsuke Hamada et al.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 35(5), 4561-4566 (2014-01-07)
This study aimed to determine the prevalence of β-catenin nuclear positivity as a prognostic factor in patients with desmoid tumors (DTs) treated with meloxicam, a cyclooxygenase-2 (COX-2) selective inhibitor. Between 2003 and 2012, consecutive 31 patients with extraabdominal, sporadic DTs
[Meloxicam: intramuscular administration in rheumatology].
E S Tsvetkova
Terapevticheskii arkhiv, 75(8), 96-97 (2003-10-03)
J Sternon et al.
Revue medicale de Bruxelles, 19(1), 29-32 (1998-04-29)
NSAID's are currently medications widely prescribed. Meloxicam is a new oxicam which has a low COX-2/COX-1 ratio, i.e. it has an inhibitory effect focused on the inflammatory proteins (COX-2) with relative saving of the homeostatic proteins (COX-1). This molecule has

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