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Merck
CN

1367561

USP

利奈唑胺

United States Pharmacopeia (USP) Reference Standard

别名:

N-[[(5S)-3-[3-氟-4-(4-吗啉基)苯基] -2-氧代-5-恶唑烷基]甲基]乙酰胺, PNU-100766, U-100766

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关于此项目

经验公式(希尔记法):
C16H20FN3O4
化学文摘社编号:
分子量:
337.35
UNSPSC Code:
41116107
NACRES:
NA.24
MDL number:
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产品名称

利奈唑胺, United States Pharmacopeia (USP) Reference Standard

InChI

1S/C16H20FN3O4/c1-11(21)18-9-13-10-20(16(22)24-13)12-2-3-15(14(17)8-12)19-4-6-23-7-5-19/h2-3,8,13H,4-7,9-10H2,1H3,(H,18,21)/t13-/m0/s1

SMILES string

CC(=O)NC[C@H]1CN(C(=O)O1)c2ccc(N3CCOCC3)c(F)c2

InChI key

TYZROVQLWOKYKF-ZDUSSCGKSA-N

grade

pharmaceutical primary standard

API family

linezolid

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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Biochem/physiol Actions

利奈唑胺是一种恶唑烷类抗菌药。它抑制细菌 mRNA的翻译和是一种弱的、可逆的、非选择性的单胺氧化酶抑制剂。
利奈唑胺是一种恶唑烷酮类抗菌药。 它与50S 亚基的细菌 23S 核糖体 RNA 上的位点结合,并阻止功能性 70S 起始复合物的形成,从而抑制细菌 mRNA 翻译。利奈唑胺也是一种弱的、可逆的非选择性单胺氧化酶抑制剂。

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

Linezolid USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Linezolid Tablets

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

pictograms

Health hazard

signalword

Danger

hcodes

pcodes

Hazard Classifications

STOT RE 1 Oral

target_organs

Bone

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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