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安全信息

1358503

USP

Leuprolide acetate

United States Pharmacopeia (USP) Reference Standard

别名:

Leuprolide acetate salt, des-Gly10-[D-Leu6]-LH-RH ethylamide, Leuprorelin

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About This Item

经验公式（希尔记法）:
C59H84N16O12 · xC2H4O2
CAS号:
74381-53-6
分子量:
1209.40 (free base basis)
MDL编号:
MFCD00167544
UNSPSC代码:
41116107
PubChem化学物质编号:
329750244
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

leuprolide

制造商/商品名称

USP

应用

pharmaceutical (small molecule)

格式

neat

储存温度

−20°C

SMILES字符串

CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc5c[nH]cn5)NC(=O)[C@@H]6CCC(=O)N6

InChI

1S/C59H84N16O12/c1-6-63-57(86)48-14-10-22-75(48)58(87)41(13-9-21-64-59(60)61)68-51(80)42(23-32(2)3)69-52(81)43(24-33(4)5)70-53(82)44(25-34-15-17-37(77)18-16-34)71-56(85)47(30-76)74-54(83)45(26-35-28-65-39-12-8-7-11-38(35)39)72-55(84)46(27-36-29-62-31-66-36)73-50(79)40-19-20-49(78)67-40/h7-8,11-12,15-18,28-29,31-33,40-48,65,76-77H,6,9-10,13-14,19-27,30H2,1-5H3,(H,62,66)(H,63,86)(H,67,78)(H,68,80)(H,69,81)(H,70,82)(H,71,85)(H,72,84)(H,73,79)(H,74,83)(H4,60,61,64)/t40-,41-,42-,43+,44-,45-,46-,47-,48-/m0/s1

InChI key

GFIJNRVAKGFPGQ-LIJARHBVSA-N

基因信息

human ... GNRHR(2798)

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相关类别

Amino Acid Sequence

Glp-His-Trp-Ser-Tyr-Leu-Leu-Arg-Pro-NHEt

一般描述

Leuprolide Acetate is a synthetic nonapeptide agonist analog of the luteinizing hormone-releasing factor. It contains not less than 97.0% and not more than 103.0 % of leuprolide, calculated on an anhydrous, acetic acid-free basis. Leuprolide Acetate USP Reference Standard is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Leuprolide Acetate USP reference standard is used to prepare standard solutions for the identification, assay, and determination of the purity of leuprolide acetate. Further information is available in monograph, Leuprolide Acetate, USP43-NF38 – 2572 of United States Pharmacopeia (USP).

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

This product is part of the USP Biologics program.
Sales restrictions may apply.

相关产品

产品编号
说明
价格

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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Leuprolide Acetate
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 42(2), 2572-2572 (2018)

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