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Merck
CN

1336500

USP

咪唑

United States Pharmacopeia (USP) Reference Standard

别名:

1,3-二氮杂-2,4-环戊二烯, 甘恶啉

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About This Item

经验公式(希尔记法):
C3H4N2
CAS号:
分子量:
68.08
Beilstein:
103853
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

pharmaceutical primary standard

蒸汽压

<1 mmHg ( 20 °C)

API类

imidazole

制造商/商品名称

USP

pKa (25 °C)

6.95

沸点

256 °C (lit.)

mp

88-91 °C (lit.)

应用

pharmaceutical (small molecule)

包装形式

neat

SMILES字符串

c1c[nH]cn1

InChI

1S/C3H4N2/c1-2-5-3-4-1/h1-3H,(H,4,5)

InChI key

RAXXELZNTBOGNW-UHFFFAOYSA-N

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

特别适用于 pH 6.2-7.8 范围内的缓冲液
Imidazole USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Clotrimazole
  • Clotrimazole Topical Solution
  • Perindopril Erbumine
  • Moexipril Hydrochloride
  • Clotrimazole Vaginal Inserts
  • Sildenafil Citrate
  • Clotrimazole Lozenges

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

Sales restrictions may apply.

警示用语:

Danger

危险声明

危险分类

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 1B - Skin Corr. 1C

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

闪点(°F)

293.0 °F - closed cup

闪点(°C)

145 °C - closed cup


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Perindopril Erbumine
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 46(4) (2023)
Clotrimazole Topical Solution
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 40(3), 1122-1122 (2016)
Clotrimazole Vaginal Inserts
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 40(5), 1123-1123 (2016)
Moexipril Hydrochloride
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 38(3), 2992-2992 (2020)
E Rosalie Witjas-Paalberends et al.
The Journal of physiology, 592(15), 3257-3272 (2014-06-15)
The first mutation associated with hypertrophic cardiomyopathy (HCM) is the R403Q mutation in the gene encoding β-myosin heavy chain (β-MyHC). R403Q locates in the globular head of myosin (S1), responsible for interaction with actin, and thus motor function of myosin.

实验方案

In the present study we demonstrate compliance of silica gel 60 F254 HPTLC plates with USP requirements, and how HPTLC plates are suitable for the Sildenafil citrate-Limit of Imidazole test.

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