InChI
1S/C20H24O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,5,7,12,16-18,21-22H,4,6,8-11H2,2H3/t16-,17-,18+,19+,20+/m1/s1
SMILES string
[H][C@]12CC[C@@]3(C)[C@@]([H])(CC[C@@]3(O)C#C)[C@]1([H])CCc4cc(O)ccc24
InChI key
BFPYWIDHMRZLRN-SLHNCBLASA-N
grade
pharmaceutical primary standard
API family
ethinyl estradiol
manufacturer/tradename
USP
mp
182-183 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
Gene Information
human ... ESR1(2099)
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General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Ethinyl estradiol USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Desogestrel and Ethinyl Estradiol Tablets
- Drospirenone and Ethinyl Estradiol Tablets
- Ethinyl Estradiol
- Ethinyl Estradiol Tablets
- Ethynodiol Diacetate and Ethinyl Estradiol Tablets
- Levonorgestrel and Ethinyl Estradiol Tablets
- Norethindrone Acetate and Ethinyl Estradiol Tablets
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 1 - Carc. 2 - Repr. 1A
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
法规信息
涉药品监管产品
此项目有
Tomás Cajthaml et al.
Environmental pollution (Barking, Essex : 1987), 157(12), 3325-3335 (2009-07-25)
Natural estrogens such as estrone, 17beta-estradiol, estriol, and the particularly recalcitrant synthetic estrogen 17alpha-ethinylestradiol used as oral contraceptive, accumulate in the environment and may give rise to health problems. The processes participating in their removal from soil, wastewater, water-sediments, groundwater-aquifer
Marie-Soleil Wagner et al.
Expert opinion on pharmacotherapy, 8(11), 1769-1777 (2007-08-10)
Many factors influence the effectiveness of contraceptive methods. Oral contraceptives are the second most popular contraceptive method after female sterilization in the US. A total of 25% of women do not use their oral contraceptives correctly; 30% of women do
Caroline Fenton et al.
Drugs, 67(12), 1749-1765 (2007-08-09)
Drospirenone 3mg with ethinylestradiol 20microg (Yaz) is a low-dose combined oral contraceptive (COC) administered in a regimen of 24 days of active tablets followed by a short hormone-free interval (4 days; 24/4 regimen). Drospirenone, unlike other synthetic progestogens used in
Per Hallgren et al.
Environmental toxicology and chemistry, 33(4), 930-936 (2014-03-13)
Endocrine-disrupting chemicals are known to alter the fitness of individual organisms via changes in growth, behavior, and reproduction. It is largely unknown, however, whether these effects cascade through the food web and indirectly affect other, less sensitive organisms. The authors
Hongjian Zhang et al.
Clinical pharmacokinetics, 46(2), 133-157 (2007-01-27)
17alpha-Ethinylestradiol (EE) is widely used as the estrogenic component of oral contraceptives (OC). In vitro and in vivo metabolism studies indicate that EE is extensively metabolised, primarily via intestinal sulfation and hepatic oxidation, glucuronidation and sulfation. Cytochrome P450 (CYP)3A4-mediated EE
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