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Merck
CN

1254508

USP

雌三醇

United States Pharmacopeia (USP) Reference Standard

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别名:
1,3,5(10)-三烯-3β,16α,17β-三醇, 16,17-二羟甾醇, 雌激素三醇
经验公式(希尔记法):
C18H24O3
CAS号:
分子量:
288.38
Beilstein:
2508172
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

estriol

制造商/商品名称

USP

mp

280-282 °C (lit.)

应用

pharmaceutical (small molecule)

格式

neat

SMILES字符串

C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1C[C@@H](O)[C@@H]2O

InChI

1S/C18H24O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h3,5,8,13-17,19-21H,2,4,6-7,9H2,1H3/t13-,14-,15+,16-,17+,18+/m1/s1

InChI key

PROQIPRRNZUXQM-ZXXIGWHRSA-N

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一般描述

Estriol is found to be a major estrogen in pregnant women. It originates in the placenta from the estrogen precursors, made by the fetal adrenal gland and liver. Estriol levels are directly related to the delivery of the fetus and serve as an index of the fetal well-being.

应用

Estriol may be used as a pharmaceutical primary standard for the quantification of the analyte in pharmaceutical formulations using chromatography techniques.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

Sales restrictions may apply.

象形图

Health hazard

警示用语:

Danger

危险声明

危险分类

Carc. 2 - Lact. - Repr. 1A

WGK

WGK 3

法规信息

监管及禁止进口产品

分析证书(COA)

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Determination of 17 $\beta$-estradiol in pharmaceutical preparation by UV spectrophotometry and high performance liquid chromatography methods
Yilmaz B and Kadioglu Y
Arabian Journal of Chemistry, 10(3), S1422-S1428 (2017)
Development and validation of a liquid chromatographic method for the simultaneous determination of estradiol, estriol, estrone, and progesterone in pharmaceutical preparations
Wilson P
Journal of AOAC (Association of Official Analytical Chemists) International, 92(3), 846-854 (2009)
"Handbook of Poylmer-Liquid Interaction Parameters and Solubility Parameters ", 27(22), 4431-4438 (2012)
Simultaneous determination of natural and synthetic estrogens by EKC using a novel microemulsion
Tripodi V, et al.
Electrophoresis, 27(22), 4431-4438 (2006)

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