跳转至内容
Merck
CN

1229922

USP

度他雄胺

United States Pharmacopeia (USP) Reference Standard

别名:

(5α,17β)-N-[2,5-双(三氟甲基)苯基] -3-氧代-4-氮杂杂芳-1-烯-17-羧酰胺

登录查看公司和协议定价


About This Item

经验公式(希尔记法):
C27H30F6N2O2
分子量:
528.53
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

pharmaceutical primary standard

API类

dutasteride

制造商/商品名称

USP

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-8°C

SMILES字符串

O=C1C=C[C@@]2(C)[C@](CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@@H]4C(NC5=CC(C(F)(F)F)=CC=C5C(F)(F)F)=O)([H])N1

InChI

1S/C27H30F6N2O2/c1-24-11-9-17-15(4-8-21-25(17,2)12-10-22(36)35-21)16(24)6-7-19(24)23(37)34-20-13-14(26(28,29)30)3-5-18(20)27(31,32)33/h3,5,10,12-13,15-17,19,21H,4,6-9,11H2,1-2H3,(H,34,37)(H,35,36)/t15-,16-,17-,19+,21+,24-,25+/m0/s1

InChI key

JWJOTENAMICLJG-QWBYCMEYSA-N

正在寻找类似产品? 访问 产品对比指南

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

应用


  • Therapeutic Applications for Benign Prostatic Hyperplasia: Dutasteride, a potent 5-alpha-reductase inhibitor, is pivotal in developing plant-derived bioactive metabolites as alternatives for treating benign prostatic hyperplasia (BPH). This research highlights the potential of dutasteride in enhancing the efficacy and safety of prostate health treatments (Krishnamoorthi et al., 2024).

  • Innovative Formulations for Hair Loss Treatment: Dutasteride is explored for its compatibility and efficacy in TrichoFoam, a natural vehicle for hair foams. This study demonstrates the potential of dutasteride in combination with other agents for treating androgenetic alopecia, providing a synergistic approach to hair loss management (Polonini et al., 2024).

  • Impact on Sexual Dysfunction: The implications of dutasteride therapy for androgenetic alopecia on sexual dysfunction are critically analyzed. This global propensity-score-matched retrospective cohort study enhances our understanding of the side effects associated with long-term use of 5-alpha-reductase inhibitors (Lauck et al., 2024).

  • Hormonal Background of Hair Loss: Dutasteride′s role is examined in the context of non-scarring alopecias, where hormonal imbalances play a significant part. This review discusses the hormonal mechanisms influenced by dutasteride, shedding light on its comprehensive effects in hair loss treatments (Owecka et al., 2024).

  • Prostate Cancer Screening and Management: The effect of 5-alpha reductase inhibitors like dutasteride on the accuracy of prostate cancer detection through MRI is scrutinized. This research underscores the importance of understanding the pharmacological actions of dutasteride in improving diagnostic and management strategies for prostate cancer (Morote et al., 2024).

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

Sales restrictions may apply.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

抱歉,我们目前尚未线上提供该产品的COA。

如需帮助,请联系 客户支持

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门