grade
pharmaceutical primary standard
vapor density
13 (vs air)
API family
curcumin
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
SMILES string
COc1cc(\C=C\C(=O)CC(=O)\C=C\c2ccc(O)c(OC)c2)ccc1O
InChI
1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+
InChI key
VFLDPWHFBUODDF-FCXRPNKRSA-N
General description
本产品按照发行药典的发行和规定提供。支持本产品的所有信息，包括安全数据表和任何产品信息传单，都是在发行药典的授权下开发和发布的。如需进一步信息和支持，请访问现行药典网站。
Biochem/physiol Actions
一种天然酚类化合物。它是有效的抗肿瘤剂，具有抗炎和抗氧化活性。除了具有化疗活性外，姜黄素还被认为是潜在的化学预防剂。它能够诱导癌细胞凋亡并抑制佛波酯诱导的蛋白激酶C（PKC）活性。据报道，它能抑制外周血单核细胞和肺泡巨噬细胞产生炎性细胞因子。它是EGFR酪氨酸激酶和IκB激酶的有效抑制剂。它能抑制诱导型一氧化氮合酶（iNOS）、环加氧酶和脂氧合酶。它易于渗透到细胞质中，在质膜、内质网和核膜等膜结构中积累。
它是一种天然酚类化合物，是姜黄的黄色来源。它是有效的抗肿瘤剂，作用于高度多样化的肿瘤特异性通路。它具有抗炎和抗氧化活性。它能够诱导癌细胞凋亡并抑制佛波酯诱导的蛋白激酶C（PKC）活性。据报道，它能抑制外周血单核细胞和肺泡巨噬细胞产生炎性细胞因子。它是EGFR酪氨酸激酶和IκB激酶的有效抑制剂。它能抑制诱导型一氧化氮合酶（iNOS）、环加氧酶（COX-2）和5-脂氧合酶（5-LOX）。
Analysis Note
这些产品仅供测试和化验使用。它们不适用于人类或动物，也不能用于诊断、治疗或治愈任何类型的疾病。
Other Notes
可能适用相应的销售限制。
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存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
Michal Heger et al.
Pharmacological reviews, 66(1), 222-307 (2013-12-26)
This review addresses the oncopharmacological properties of curcumin at the molecular level. First, the interactions between curcumin and its molecular targets are addressed on the basis of curcumin's distinct chemical properties, which include H-bond donating and accepting capacity of the
Anggakusuma et al.
Gut, 63(7), 1137-1149 (2013-08-02)
Hepatitis C virus (HCV) infection causes severe liver disease and affects more than 160 million individuals worldwide. People undergoing liver organ transplantation face universal re-infection of the graft. Therefore, affordable antiviral strategies targeting the early stages of infection are urgently
Bharat B Aggarwal et al.
Molecular nutrition & food research, 57(9), 1529-1542 (2013-07-13)
Turmeric, a dried powder derived from the rhizome of Curcuma longa, has been used for centuries in certain parts of the world and has been linked to numerous biological activities including antioxidant, anti-inflammatory, anticancer, antigrowth, anti-arthritic, anti-atherosclerotic, antidepressant, anti-aging, antidiabetic
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 1151855-30MG | 04061833868676 |